ArticleArXiv2025
Rodent Breathing Waveforms in ApoE Rats: Statistical and Entropic Differentiation.
Article in ArXiv, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Apolipoprotein E (ApoE) gene variations are involved in lipid metabolism and cholesterol transport, with the ApoE4 allele being a known risk factor associated with neurodegenerative conditions later in life. Emerging evidence suggests these genetic variations may also influence respiratory function and vitality. However, the specific impact of different ApoE genotypes on breathing patterns remains largely unexplored. This work investigates differences in breathing waveform characteristics and entropy statistics derived from plethysmography (PLETH) data between rat models possessing two distinct ApoE genotypes (referred to herein as gene59 and gene95). Findings reveal significant distributional differences in common plethysmography metrics and approximate entropy between the two genotypes, observed during both active and resting states. Additionally, the study examines the transient impact of sighs (deep breaths) on these breathing metrics, demonstrating that entropy and other measures are altered in the breaths immediately following a sigh.
Identifiers
40406078PMC12097682What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.