Evidence map›Paper›PMID 40405986›Full record

ArticleJDS communications2025

Differential effects of 3-nitrooxypropanol supplementation on milk fatty acid profiles in 3 different dairy breeds.

Gayani M S Lokuge, Nicolaj I Nielsen, Morten Maigaard, Peter Lund, Lotte Bach Larsen, Lars Wiking, Nina Aagaard Poulsen

Abstract read
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Article in JDS communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gayani M S LokugeDepartment of Food Science, Aarhus University, Agro Food Park 48, DK-8200 Aarhus N, Denmark.
Nicolaj I NielsenSEGES Innovation P/S, Agro Food Park 15, DK-8200 Aarhus N, Denmark.
Morten MaigaardDepartment of Animal and Veterinary Sciences, Aarhus University, AU Viborg-Research Centre Foulum, Blichers Allé 20, DK-8830 Tjele, Denmark.
Peter LundDepartment of Animal and Veterinary Sciences, Aarhus University, AU Viborg-Research Centre Foulum, Blichers Allé 20, DK-8830 Tjele, Denmark.
Lotte Bach LarsenDepartment of Food Science, Aarhus University, Agro Food Park 48, DK-8200 Aarhus N, Denmark.
Lars WikingDepartment of Food Science, Aarhus University, Agro Food Park 48, DK-8200 Aarhus N, Denmark.
Nina Aagaard PoulsenDepartment of Food Science, Aarhus University, Agro Food Park 48, DK-8200 Aarhus N, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

3-Nitrooxypropanol (3-NOP) is a promising and approved antimethanogenic feed additive in dairy farming. The objective of this study was to evaluate breed-specific variation in milk fatty acids (FA) following 3-NOP supplementation. Milk FA composition was analyzed from 3 studies using Danish Holstein (DH), Danish Jersey (DJ), and Danish Red (DR) dairy cows respectively, fed control or 3-NOP supplemented diets. The 3-NOP was supplemented at a dose of 60 mg/kg feed DM. Bulk milk samples were analyzed for milk FA by GC flame ionization detection. The 3-NOP supplemented diets increased the proportion of short-chain fatty acids (SCFA) and decreased the proportion of C16:0 in the milk of DH cows. A similar tendency in milk FA composition induced by 3-NOP was observed in DJ cows; however, the extent of these changes was less pronounced, and no changes were observed in milk FA from DR cows. Indirect comparison among the breeds showed a higher proportion of SCFA in milk from DJ cows, a higher proportion of medium-chain FA in DR cows and a higher proportion of long-chain FA in DH cows. The effect of 3-NOP on milk FA composition appears to vary between breeds; however, this variation may also be influenced by differences in feeding regimens between breeds, making further studies worthwhile to better understand these interactions.

Identifiers

PMID40405986
PMCPMC12094046

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.