Evidence map›Paper›PMID 40405938›Full record

ArticleJournal of medicine and life2025

Rendu-Osler disease, a cause of recurrent epistaxis: a case report.

Raluca Oana Pulpă, Cătălina Voiosu, Ruxandra Oana Aliuș, Irina Gabriela Ioniță, Andreea Rusescu, Răzvan Hainăroșie, Viorel Zainea

Abstract readCase Reports
In one paragraph

Article in Journal of medicine and life, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Raluca Oana PulpăENT Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Cătălina VoiosuENT Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Ruxandra Oana AliușENT Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Irina Gabriela IonițăENT Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Andreea RusescuENT Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Răzvan HainăroșieENT Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Viorel ZaineaENT Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rendu-Osler disease is a rare, autosomal dominant vascular malformation disorder with diverse clinical manifestations. It commonly presents with recurrent epistaxis, iron deficiency, and secondary anemia. The condition affects small vessels in the nasal, oral, and gastrointestinal mucosa, the skin of the face, lips, and fingertips, and solid organs. This article discusses general and specific manifestations of the disease, along with its general and particular management. A case presentation is included to demonstrate that treatment must be individualized, taking into account all aspects of the condition, including local and systemic manifestations, comorbidities, and the patient's chronic treatment.

Indexed as

EpistaxisTelangiectasia, Hereditary HemorrhagicFemaleHumansMaleRecurrenceepistaxisRendu-Osler-Webertelangiectasia

Identifiers

PMID40405938
PMCPMC12094311

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.