Evidence map›Paper›PMID 40405929›Full record

ArticleJournal of medicine and life2025

Prognostic factors and relapse in nodal vs. extranodal non-Hodgkin lymphoma of the ENT region: a prospective cohort study.

Raluca Morar, Norberth-Istvan Varga, Claudia Raluca Balasa Virzob, Nicolae Constantin Balica, Ioana Delia Horhat, Alexandru Chioreanu, Oana Silvana Sarau, Sonia Tanasescu, Razvan Susan, Ion Cristian Mot

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Article in Journal of medicine and life, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Raluca MorarDepartment of General Medicine, Doctoral School, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.
Norberth-Istvan VargaDepartment of General Medicine, Doctoral School, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.
Claudia Raluca Balasa VirzobDepartment of Clinic Nursing, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.
Nicolae Constantin BalicaENT Department, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.
Ioana Delia HorhatENT Department, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.
Alexandru ChioreanuDepartment of Otorhinolaryngology, Vasile Goldis Western University of Arad, Arad, Romania.
Oana Silvana SarauHematology Department, Municipal Emergency Clinical Hospital, Timisoara, Romania.
Sonia TanasescuDepartment of Pediatrics, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.
Razvan SusanDepartment of Family Medicine, Centre for Preventive Medicine, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.
Ion Cristian MotENT Department, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-Hodgkin Lymphoma (NHL) arising from the ear, nose, and throat (ENT) region presents unique challenges with regard to diagnosis and treatment. This study investigated the clinical characteristics, prognostic factors, and relapse patterns in patients with NHL originating from lymph nodes (nodal NHL) or other extranodal structures, aiming to identify factors associated with relapse between these two groups. This prospective cohort study included 50 patients diagnosed with NHL in the ENT region at a tertiary hospital in South-Western Romania between 2019 and 2021. Patients were categorized as having nodal or extranodal disease based on histopathological examination and were followed for three years to assess disease evolution, including relapse. Cox proportional hazards regression analysis was employed to identify factors associated with relapse-free survival. Extranodal NHL was associated with a significantly higher prevalence of multiple-site involvement compared to nodal NHL (53.3% vs. 30%,

Indexed as

Lymph NodesLymphoma, Non-HodgkinNeoplasm Recurrence, LocalAdultAgedFemaleHumansMaleMiddle AgedPrognosisProspective StudiesDLBCL, Diffuse Large B-cell LymphomaEarsENTENT, Ears, Nose and ThroatENT lymphomaextranodal lymphomaHR, Hazard Ratiolymph nodeNHL, Non-Hodgkin LymphomaNHL prognosticNHL relapsesNon-Hodgkin LymphomaNose and Throat

Identifiers

PMID40405929
PMCPMC12094306

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.