Evidence map›Paper›PMID 40405928›Full record

ReviewJournal of medicine and life2025

Optimizing outcomes of partial nephrectomy in patients with tumors in solitary kidneys: a non-systematic review.

Stelian Ianiotescu, Constantin Gingu, Alexandru Iordache, Adrian Preda, Osama Salloum, Irina Balescu, Nicolae Bacalbasa, Ioanel Sinescu

Abstract readReview
In one paragraph

Review in Journal of medicine and life, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stelian IaniotescuCarol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Constantin GinguCenter of Uronephrology and Kidney Transplantation, Fundeni Clinical Institute, Bucharest, Romania.
Alexandru IordacheDepartment of Nephrology, Urology, Immunology and Immunology of Transplant, Dermatology, Allergology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Adrian PredaDepartment of Nephrology, Urology, Immunology and Immunology of Transplant, Dermatology, Allergology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Osama SalloumDepartment of Nephrology, Urology, Immunology and Immunology of Transplant, Dermatology, Allergology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Irina BalescuDepartment of Surgery, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Nicolae BacalbasaDepartment of Surgery, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Ioanel SinescuCenter of Uronephrology and Kidney Transplantation, Fundeni Clinical Institute, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review consolidates recent evidence on managing renal cell carcinoma (RCC) in patients with solitary kidneys. It provides a comprehensive discussion of evolving strategies in partial nephrectomy-including open, laparoscopic, and particularly robot-assisted partial nephrectomy (RAPN)-along with thermal and advanced ablative therapies, non-surgical options (such as stereotactic ablative body radiotherapy [SABR] and active surveillance [AS]), and emerging neoadjuvant systemic treatments with tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs). In addition, the integration of artificial intelligence (AI) for preoperative planning, intraoperative guidance, and postoperative outcome prediction is discussed. Given the limited renal reserve in these patients, preserving functional renal parenchyma is paramount. This multidisciplinary review synthesizes evidence from 2018 to the present and is supported by 70 contemporary references.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsNephrectomySolitary KidneyHumansRobotic Surgical ProceduresTreatment Outcomeartificial intelligenceimmune checkpoint inhibitorsnephron-sparing surgerypostoperative outcome predictionpreoperative planningradiofrequency ablationrenal cell carcinomaSolitary kidneystereotactic ablative body radiotherapythermal ablation

Identifiers

PMID40405928
PMCPMC12094310

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.