Evidence map›Paper›PMID 40405888›Full record

ArticleAcute medicine & surgery

Performance of Universal TOR rule for out-of-hospital cardiac arrest in the Pan-Asian Resuscitation Outcomes Study.

Atsunori Onoe, Kentaro Kajino, Ng Wei Ming, Hideharu Tanaka, Takashi Tagami, Hyun Ho Ryu, Chih-Hao Lin, Marcus Eng Hock Ong, Yasuyuki Kuwagata, P Khruekarnchana and 14 more

Abstract read
In one paragraph

Article in Acute medicine & surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Atsunori OnoeDepartment of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.ORCID https://orcid.org/0009-0007-7421-9311
Kentaro KajinoDepartment of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.ORCID https://orcid.org/0000-0003-1735-2902
Ng Wei MingDepartment of Emergency Medicine Ng Teng Fong General Hospital Singapore Singapore.
Hideharu TanakaGraduate School of EMS System Kokushikan University Tokyo Japan.ORCID https://orcid.org/0000-0003-4565-0026
Takashi TagamiDepartment of Emergency and Disaster Medicine The Jikei University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0001-6953-1932
Hyun Ho RyuDepartment of Emergency Medicine Chonnam National University Hospital Gwangju Korea.
Chih-Hao LinDepartment of Emergency Medicine National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan.
Marcus Eng Hock OngDepartment of Emergency Medicine Singapore General Hospital Singapore Singapore.
Yasuyuki KuwagataDepartment of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.
P KhruekarnchanaDepartment of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.
N E DoctorDepartment of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.
L P ThamDepartment of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.
Myc ChiaDepartment of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.
H N GanDepartment of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.
Bsh LeongDepartment of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.
Drh MaoDepartment of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.
R RaoDepartment of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.
M VimalDepartment of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.
B VelascoDepartment of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.
S A ZhouDepartment of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.
N KhanDepartment of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.
D A NguyenDepartment of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.
Y Y NgDepartment of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.
A ShaliniDepartment of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Out-of-hospital cardiac arrest (OHCA) is a public health problem. The Universal Termination of Resuscitation (TOR) rule attempts to reduce the rate of futile transports. The aim of this study was to examine and compare the performance of the TOR rule for OHCA cases in Japan, Korea, Singapore, and Taiwan, where the TOR rule has not been implemented. Methods: This retrospective cohort study examined data from January 1, 2009, to June 30, 2018, reported to the Pan-Asian Resuscitation Outcomes Study. We included patients with nontraumatic OHCA in the four countries and compared the performance of the Universal TOR rule in these countries. Results: The number of eligible cases was 173,629. The performance of the Universal TOR rule for cases of neurologically poor survival showed a positive predictive value of more than 0.99 in all four countries. However, specificity differed among them: Japan 0.938, 95% confidence interval (CI): 0.931-0.945; Korea 0.922, 95% CI: 0.901-0.939; Singapore 0.985, 95% CI: 0.964-0.993; and Taiwan 0.773, 95% CI: 0.736-0.807. Conclusion: The positive predictive value of neurologically poor survival in cases meeting the Universal TOR rule among the four countries was greater than 99%. However, the specificity of these cases that met the Universal TOR rule differed among the four countries. Therefore, further refinement of the Universal TOR rule may be needed for local implementation. The quality of resuscitation in an out-of-hospital setting may also impact survival and neurological outcomes and needs to be considered in any implementation of TOR.

Indexed as

cerebral performance categoryoutcomeout‐of‐hospital cardiac arrestUniversal Termination of Resuscitation rule

Identifiers

PMID40405888
PMCPMC12096366

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.