Evidence map›Paper›PMID 40405785›Full record

ArticleScience progress

A case of suppurative tonsillitis as a complication of acute infectious mononucleosis.

Changqing Wang, Lifu Duan, Peilin Li, Wenmin Zhao, Xianbao Cao

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In one paragraph

Article in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Changqing WangDepartment of Otolaryngology, People's Hospital of Xishuangbanna Dai Nationality Autonomous Prefecture, Yunnan, China.ORCID 0000-0001-7679-4837
Lifu DuanDepartment of Otolaryngology, Zigong First People's Hospital, Sichuan, China.
Peilin LiDepartment of Otolaryngology, People's Hospital of Xishuangbanna Dai Nationality Autonomous Prefecture, Yunnan, China.
Wenmin ZhaoDepartment of Otolaryngology, People's Hospital of Xishuangbanna Dai Nationality Autonomous Prefecture, Yunnan, China.
Xianbao CaoDepartment of Otolaryngology-Head and Neck Surgery, The First People's Hospital of Yunnan Province, Kunming, Yunnan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious mononucleosis (IM) is a benign lymphoproliferative disorder primarily caused by the Epstein-Barr virus (human gamma-herpesvirus 4) and most commonly affects 15-24-year-old individuals. Spontaneous splenic ruptures occur in 0.1% to 0.5% of patients with IM and can be life-threatening despite reports of suppurative processes involving the tonsils, such as intra-amygdala or peritonsillar abscesses. However, these rare complications can easily be misdiagnosed as acute suppurative tonsillitis caused by typical bacterial infection. This paper reports a case of a teenager with IM and concurrent suppurative tonsillitis, who was initially misdiagnosed with acute bacterial tonsillitis and failed to respond to antibiotic treatment. Examination confirmed IM combined with suppurative tonsillitis. Notably, his symptoms improved significantly after antiviral treatment. Therefore, we suggest that IM-complicating suppurative tonsillitis should be excluded when acute suppurative tonsillitis does not respond to antibiotic treatment and antiviral treatment strategies are urgently needed to avoid serious life-threatening complications.

Indexed as

Infectious MononucleosisTonsillitisAcute DiseaseAdolescentAnti-Bacterial AgentsAntiviral AgentsHerpesvirus 4, HumanHumansMaleSuppurationAnti-Bacterial AgentsAntiviral AgentsEpstein–Barr virus infectionsherpesvirus 4humanInfectious mononucleosisoropharynxtonsillitis

Identifiers

PMID40405785
PMCPMC12103673

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.