Evidence map›Paper›PMID 40405769›Full record

ArticleHuman brain mapping2025

Characterization of Portable Ultra-Low Field MRI Scanners for Multi-Center Structural Neuroimaging.

Emil Ljungberg, Francesco Padormo, Megan Poorman, Petter Clemensson, Niall Bourke, John C Evans, James Gholam, Irene Vavasour, Shannon H Kollind, Samson L Lafayette and 24 more

Abstract readMulticenter Study
In one paragraph

Article in Human brain mapping, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Repeatability and reproducibility of rapid TImaging neuroscience (Cambridge, Mass.) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Emil LjungbergDepartment of Medical Radiation Physics, Lund University, Lund, Sweden.ORCID 0000-0003-1456-7967
Francesco PadormoHyperfine Inc, Guilford, Connecticut, USA.ORCID 0000-0001-5699-2692
Megan PoormanHyperfine Inc, Guilford, Connecticut, USA.ORCID 0000-0001-5474-8776
Petter ClemenssonDepartment of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0002-5238-9084
Niall BourkeDepartment of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
John C EvansCUBRIC, Cardiff School of Psychology, Cardiff University, Cardiff, UK.ORCID 0000-0002-6619-4245
James GholamCUBRIC, Cardiff School of Psychology, Cardiff University, Cardiff, UK.
Irene VavasourDepartment of Radiology, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0001-9286-0953
Shannon H KollindDepartment of Medicine (Neurology), University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0003-1362-1968
Samson L LafayettePerinatal Imaging & Health, King's College London, London, UK.
Carly BennallickDepartment of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Kirsten A DonaldDivision of Developmental Paediatrics, Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, Cape Town, South Africa.ORCID 0000-0002-0276-9660
Layla E BradfordDivision of Developmental Paediatrics, Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, Cape Town, South Africa.ORCID 0000-0002-5195-9081
Beatrice LenaC.J. Gorter MRI Center, Radiology Department, Leids Universitair Medisch Centrum, Leiden, the Netherlands.ORCID 0000-0001-9283-5918
Maclean VokhiwaTraining & Research Unit of Excellence (TRUE), Zomba, Malawi.
Talat ShamaInfectious Diseases Division, International Centre for Diarrheal Disease Research, Dhaka, Bangladesh.
Jasmine SiewLaboratories of Cognitive Neuroscience, Division of Developmental Medicine, Department of Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.
Lydia SekoliInstitute for Cellular and Molecular Medicine, Department of Medical Immunology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
Jeanne van RensburgInstitute for Cellular and Molecular Medicine, Department of Medical Immunology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
Michael S PepperInstitute for Cellular and Molecular Medicine, Department of Medical Immunology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.ORCID 0000-0001-6406-2380
Amna KhanDepartment of Paediatrics & Child Health, The Aga Khan University, Karachi, Pakistan.
Akber MadhwaniDepartment of Paediatrics & Child Health, The Aga Khan University, Karachi, Pakistan.
Frank A BandaUniversity of North Carolina Global Projects, Lusaka, Zambia.
Mwila L MwilaUniversity of North Carolina Global Projects, Lusaka, Zambia.
Adam R CassidyBotswana Harvard Health Partnership, Gaborone, Botswana.ORCID 0000-0001-8938-1265
Kebaiphe MoabiBotswana Harvard Health Partnership, Gaborone, Botswana.
Dolly SephiBotswana Harvard Health Partnership, Gaborone, Botswana.
Richard A BoakyeKintampo Health Research Centre (KHRC), Kintampo, Ghana.ORCID 0009-0004-4186-0805
Kenneth A Ae-NgibiseKintampo Health Research Centre (KHRC), Kintampo, Ghana.ORCID 0000-0001-5638-4814
Kwaku P AsanteKintampo Health Research Centre (KHRC), Kintampo, Ghana.ORCID 0000-0001-9158-351X
William J HollanderCaliberMRI, Boulder, Colorado, USA.
Todor KaraulanovCaliberMRI, Boulder, Colorado, USA.
Steven C R WilliamsDepartment of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Sean DeoniMNCH D&T, Bill & Melinda Gates Foundation, Seattle, WA, USA.

Funding

Bill and Melinda Gates Foundation INV-045214Bill and Melinda Gates Foundation INV-047888Gates Foundation INV-023509Gates Foundation INV-041062Wellcome Leap 222076/Z/20/Z
6 · The paper itself

Abstract

The lower infrastructure requirements of portable ultra-low field MRI (ULF-MRI) systems have enabled their use in diverse settings such as intensive care units and remote medical facilities. The UNITY Project is an international neuroimaging network harnessing this technology, deploying portable ULF-MRI systems globally to expand access to MRI for studies into brain development. Given the wide range of environments where ULF-MRI systems may operate, there are external factors that might influence image quality. This work aims to introduce the quality control (QC) framework used by the UNITY Project to investigate how robust the systems are and how QC metrics compare between sites and over time. We present a QC framework using a commercially available phantom, scanned with 64 mT portable MRI systems at 17 sites across 12 countries on four continents. Using automated, open-source analysis tools, we quantify signal-to-noise, image contrast, and geometric distortions. Our results demonstrated that the image quality is robust to the varying operational environment, for example, electromagnetic noise interference and temperature. The Larmor frequency was significantly correlated to room temperature, as was image noise and contrast. Image distortions were less than 2.5 mm, with high robustness over time. Similar to studies at higher field, we found that changes in pulse sequence parameters from software updates had an impact on QC metrics. This study demonstrates that portable ULF-MRI systems can be deployed in a variety of environments for multi-center neuroimaging studies and produce robust results.

Indexed as

BrainMagnetic Resonance ImagingNeuroimagingHumansImage Processing, Computer-AssistedPhantoms, ImagingQuality ControlSignal-To-Noise Ratiomulti‐centerneuroimagingphantomquality controlultra‐low field MRI

Identifiers

PMID40405769
PMCPMC12099222

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.