Evidence map›Paper›PMID 40405680›Full record

ArticleTechnology in cancer research & treatment

Neuregulin 4: A Key Regulator in Suppressing Lung Adenocarcinoma Progression.

Shufan Zhang, Tianhan Xu, Simeng Li, Liming Tang, Dongmei Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shufan ZhangDepartment of Gastrointestinal Surgery, The Third Affiliated Hospital of Nanjing Medical University, Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou Medical Center, Nanjing Medical University, Changzhou 213000, P. R. C.
Tianhan XuDepartment of Gastrointestinal Surgery, The Third Affiliated Hospital of Nanjing Medical University, Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou Medical Center, Nanjing Medical University, Changzhou 213000, P. R. C.
Simeng LiDepartment of Gastrointestinal Surgery, The Third Affiliated Hospital of Nanjing Medical University, Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou Medical Center, Nanjing Medical University, Changzhou 213000, P. R. C.
Liming TangDepartment of Gastrointestinal Surgery, The Third Affiliated Hospital of Nanjing Medical University, Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou Medical Center, Nanjing Medical University, Changzhou 213000, P. R. C.
Dongmei WangDepartment of Gastrointestinal Surgery, The Third Affiliated Hospital of Nanjing Medical University, Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou Medical Center, Nanjing Medical University, Changzhou 213000, P. R. C.ORCID 0000-0002-9922-5626

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLung adenocarcinoma remains a significant public health concern, necessitating novel therapeutic approaches. Neuregulin 4 (NRG4), a secreted protein of the epidermal growth factor family, is recognized for its roles in metabolic regulation and anti-inflammatory processes, suggesting therapeutic potential across various diseases. However, its specific function in lung adenocarcinoma progression is not well elucidated.

Indexed as

Adenocarcinoma of LungLung NeoplasmsNeuregulinsAnimalsBiomarkers, TumorCell Line, TumorCell MovementCell ProliferationDisease Models, AnimalDisease ProgressionEpithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticHumansMiceXenograft Model Antitumor AssaysBiomarkers, Tumorneuregulin-4Neuregulinsextracellular matrixlung adenocarcinomaNRG4

Identifiers

PMID40405680
PMCPMC12158796

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.