Evidence map›Paper›PMID 40405531›Full record

ArticlePhysiological reports2025

Oscillometry with or without spirometry for methacholine testing.

Cyndi Henry, Magali Boucher, Marie-Ève Boulay, Andréanne Côté, Ynuk Bossé

Abstract read
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Oscillometry for the diagnosis of asthma in children: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Article
  3. The testosterone paradox in asthma.Frontiers in allergy · 2026
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cyndi HenryInstitut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ), Université Laval, Québec City, Québec, Canada.
Magali BoucherInstitut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ), Université Laval, Québec City, Québec, Canada.
Marie-Ève BoulayInstitut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ), Université Laval, Québec City, Québec, Canada.
Andréanne CôtéInstitut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ), Université Laval, Québec City, Québec, Canada.
Ynuk BosséInstitut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ), Université Laval, Québec City, Québec, Canada.ORCID 0000-0002-2023-3130

Funding

Gouvernement du Canada | Canadian Institutes of Health Research (IRSC) 508356-202209PJTGouvernement du Canada | Natural Sciences and Engineering Research Council of Canada (NSERC) RGPIN-2020-06355
6 · The paper itself

Abstract

Oscillometry is proposed as a complementary technique to spirometry for methacholine testing. Yet, before being prescribed in conjunction with spirometry, the extent by which the oscillometric readouts are influenced by spirometric maneuvers, especially the deep inspirations, will need to be determined. Herein, 16 very mild-to-mild asthmatics underwent two methacholine challenges on separate visits. On visit 1, the response was tracked by both oscillometry and spirometry, and the challenge was stopped at the provocative concentration causing a decline in forced expiratory volume in 1 s of at least 20%. The same concentration regimen was used on visit 2, but the response was tracked by oscillometry only. The results demonstrated that, except for resistance at 19 Hz, the changes in all oscillometric readouts were greater in the challenge without spirometry (p ≤ 0.02). The maximal change in reactance at 5 Hz (X

Indexed as

AsthmaBronchial Provocation TestsBronchoconstrictor AgentsMethacholine ChlorideOscillometrySpirometryAdultFemaleForced Expiratory VolumeHumansMaleMiddle AgedBronchoconstrictor AgentsMethacholine Chlorideasthmamethacholine testingoscillometryreactancerespiratory mechanicsspirometry

Identifiers

PMID40405531
PMCPMC12098963

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.