ArticlePhysiological reports2025
Analysis of the effect of 6-Hz binaural beats on electroencephalographic and autonomic parameters of healthy individuals: An exploratory study.
Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- The impact of sound intervention on sleep quality and stress levels in college students: a randomized controlled trial.Frontiers in psychology · 2026Article
- Psychophysiological effects of low-frequency sound mediated by room size, room shape, and stimulus duration.Frontiers in cognition · 2026Article
- Analysis of the effect of 6-Hz binaural beats on electroencephalographic and autonomic parameters of healthy individuals: An exploratory study.Physiological reports · 2025Article
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Authors and funding
12 authors.
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Abstract
Binaural beats (BB) are a non-acoustic perception generated when two pure tones with a slight mismatch in frequency are presented separately to each ear. The aims of our study were to analyze the ability of 6-Hz BB in entraining cortical activity, altering cortical connectivity, and influencing Autonomic Nervous System (ANS) functioning to evaluate, in future studies, their application in improving compliance with Non-Invasive Ventilation (NIV) in critically ill patients. Twenty healthy volunteers underwent four 10-min experimental auditory conditions while their electroencephalographic and polygraphic activities were recorded: Resting-state, 6-Hz BB, 6-Hz monaural beats (MB), and random noise (RN). Frequency analysis and analysis of lagged-phase connectivity were computed through eLORETA. Heart rate variability, respiratory rate, and pulse transit time were analyzed as indicators of ANS activity. 6-Hpz BB entrained cortical activity at the beat frequency in the left cuneus and precuneus, in contrast with other experimental conditions. All auditory stimuli increased the interhemispheric lagged-phase connectivity between auditory cortices. Contrary to MB and RN, BB induced only minimal changes in ANS parameters. 6-Hz BB is effective in entraining cortical activity and induces only minimal changes in ANS parameters. These findings support the future use of BB as tools for increasing NIV compliance.
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