Evidence map›Paper›PMID 40405396›Full record

ArticleVirulence2025

A lymphostatin homologue from

Elizabeth A Blackburn, Cosmin Chintoan-Uta, Andrew G Bease, Maarten W Tuijtel, Max Hateley, Martin Wear, David Longbottom, Robin Cassady-Cain, Mark P Stevens

Abstract read
In one paragraph

Article in Virulence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Complete deletion of theInfection and immunity · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elizabeth A BlackburnThe Edinburgh Protein Production Facility, University of Edinburgh, Edinburgh, UK.
Cosmin Chintoan-UtaThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
Andrew G BeaseThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
Maarten W TuijtelThe Edinburgh Protein Production Facility, University of Edinburgh, Edinburgh, UK.
Max HateleyThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
Martin WearThe Edinburgh Protein Production Facility, University of Edinburgh, Edinburgh, UK.
David LongbottomThe Moredun Research Institute, Pentland Science Park, Edinburgh, UK.
Robin Cassady-CainThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
Mark P StevensThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.ORCID 0000-0003-2174-5039

Funding

Biotechnology and Biological Sciences Research Council BBS/E/RL/230002BBiotechnology and Biological Sciences Research Council BBS/E/RL/230002CWellcome TrustWellcome Trust 087658/Z/08/ZWellcome Trust 101527/Z/13/Z
6 · The paper itself

Abstract

Pathogens frequently produce proteins to evade or inhibit host immune responses. One such protein is lymphostatin from attaching and effacing

Indexed as

Bacterial ProteinsCell ProliferationChlamydiaInterferon-gammaT-LymphocytesAnimalsCattleChlamydia InfectionsCloning, MolecularLymphocyte ActivationBacterial ProteinsInterferon-gammaChlamydiaEscherichia coliIFNγinhibitionlymphocytelymphostatin

Identifiers

PMID40405396
PMCPMC12118415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.