Evidence map›Paper›PMID 40405030›Full record

ReviewClinical reviews in allergy & immunology2025

Macrophage-Centric Immunometabolic Crosstalk in Alopecia Areata Pathogenesis: Mechanisms and Therapeutic Implications.

Xu Liu, Xiuzu Song

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical reviews in allergy & immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xu LiuDepartment of Dermatology, Hangzhou Third People's Hospital, West Lake Ave 38, Hangzhou, 310009, People's Republic of China.
Xiuzu SongDepartment of Dermatology, Hangzhou Third People's Hospital, West Lake Ave 38, Hangzhou, 310009, People's Republic of China. songxiuzu@sina.com.

Funding

National Natural Science Foundation of China 82473549Science and Technology Major Project of Zhejiang Province and the State Administration of Traditional Chinese Medicine GZY-ZJ-KJ-23035
6 · The paper itself

Abstract

Although alopecia areata (AA) is recognized as a hair loss disorder stemming from the dysregulation of cutaneous immune homeostasis, its precise pathogenesis still remains elusive. The collapse of hair follicle (HF) immune privilege (IP), leading to immune cell-mediated attack on the hair follicle, is currently the widely accepted fundamental mechanism of AA. Among the immune cells studied in this context, CD8

Indexed as

Alopecia AreataHair FollicleMacrophagesAnimalsDisease SusceptibilityHumansT-Lymphocytes, RegulatoryAlopecia areataCutaneous immune homeostasisHair follicle

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.