Evidence map›Paper›PMID 40404999›Full record

ArticleCardiovascular and interventional radiology2025

One-year Clinical Outcomes and Predictors of Distal Embolization After JETSTREAM™ Atherectomy for Calcified Femoropopliteal Artery Lesions: Results From the JET-FORWARD Study.

Shunsuke Kojima, Takahiro Tokuda, Akiko Tanaka, Naoki Yoshioka, Kohei Yamaguchi, Takashi Yanagiuchi, Kenji Ogata, Tatsuro Takei, Tatsuya Nakama, LEADers PAD investigators

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Cardiovascular and interventional radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Atherectomy With Multimodal Embolic Protection for Severely Calcified Femoropopliteal Lesions.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shunsuke KojimaDepartment of Cardiology, Tokyo Bay Urayasu Ichikawa Medical Center, 3-4-32, Todaijima, Urayasu, Chiba, 279-0001, Japan. shun.reon@gmail.com.ORCID http://orcid.org/0000-0001-7764-2165
Takahiro TokudaDepartment of Cardiology, Nagoya Heart Center, Nagoya, Japan.
Akiko TanakaDepartment of Cardiology, Sendai Kousei Hospital, Sendai, Japan.
Naoki YoshiokaDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.
Kohei YamaguchiDepartment of Cardiology, Saiseikai Yokohama City Eastern Hospital, Yokohama, Japan.
Takashi YanagiuchiDepartment of Cardiology, Rakuwakai Otowa Hospital, Kyoto, Japan.
Kenji OgataDepartment of Cardiology, Miyazaki Medical Association Hospital, Miyazaki, Japan.
Tatsuro TakeiDepartment of Cardiology, Tenyoukai Central Hospital, Kagoshima, Japan.
Tatsuya NakamaDepartment of Cardiology, Tokyo Bay Urayasu Ichikawa Medical Center, 3-4-32, Todaijima, Urayasu, Chiba, 279-0001, Japan.
LEADers PAD investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to identify predictors of distal embolization following JETSTREAM™ atherectomy for calcified femoropopliteal lesions and evaluate 1-year clinical outcomes in a real-world setting. MATERIALS AND

methodsWe analyzed data from 109 patients with 121 calcified femoropopliteal lesions who underwent JETSTREAM™ atherectomy therapy between October 2022 and December 2023 as part of the JET-FORWARD study, a retrospective, single-arm, multicenter study. Distal embolization incidence and risk factors were the primary focus, while 1-year primary patency served as efficacy outcome measures. Safety outcomes also included mortality and major target limb amputation.

resultsThe mean lesion length was 15.5 ± 9.4 cm, and the technical success rate-defined as residual stenosis less than 30% and absence of grade C or higher dissection post-procedure-was 93.4%. Angiographically significant distal embolization occurred in 35.5% of cases during the index procedure. On multivariate analysis, poor tibial runoff (≤ 1 tibial artery), severe small artery disease, nodular calcification, and debulking lengths > 10 cm were independent predictors of distal embolization. The 1-month mortality and 1-year limb salvage rates were 2.8% and 98.9%, respectively. The 1-year primary patency rate was 88.9%.

conclusionAngiographically significant distal embolization occurred in 35.5% of cases with JETSTREAM atherectomy, while 1-year outcomes remained favorable in treating femoropopliteal lesions. This study also identified four predictors of distal embolization. Thus, careful risk factor evaluation and patient selection are essential during atherectomy.

Indexed as

AtherectomyEmbolismFemoral ArteryPeripheral Arterial DiseasePopliteal ArteryVascular CalcificationAgedAged, 80 and overFemaleHumansLimb SalvageMaleMiddle AgedRetrospective StudiesRisk FactorsTreatment OutcomeDistal embolizationEndovascular therapyJETSTREAM™ atherectomy deviceLower extremity arterial diseaseProtection deviceRisk factors

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.