Evidence map›Paper›PMID 40404836›Full record

Observational studyScientific reports2025

Sex differences in factors affecting spinopelvic sagittal alignment and balance: a cross-sectional observational study in a Japanese community.

Takaaki Nakano, Tetsushi Oyama, Kanichiro Wada, Kairo Wada, Gentaro Kumagai, Yoshiro Nitobe, Kotaro Aburakawa, Yasuyuki Ishibashi

Abstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Takaaki NakanoDepartment of Orthopedic Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan.
Tetsushi OyamaDepartment of Orthopedic Surgery, Aomori Rosai Hospital, Hachinohe, Japan.
Kanichiro WadaDepartment of Orthopedic Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan. wadak39@hirosaki-u.ac.jp.
Kairo WadaDepartment of Orthopedic Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan.
Gentaro KumagaiDepartment of Orthopedic Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan.
Yoshiro NitobeDepartment of Orthopedic Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan.
Kotaro AburakawaDepartment of Orthopedic Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan.
Yasuyuki IshibashiDepartment of Orthopedic Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan.

Funding

Japan Science and Technology Agency JPMJCS1302
6 · The paper itself

Abstract

Understanding how age and sex affect spinopelvic sagittal alignment is important for preventing the progression of adult spinal deformity and optimizing treatment. Here, we analyzed sex differences in age-related changes in spinopelvic sagittal alignment and balance in a Japanese community. Healthy adults (210 men and 300 women) ranging in age from their 20-80 s who participated in a general population health examination were categorized into age groups by decade according to sex. The association between changes in sagittal spinal alignment and balance, vertebral fracture, bone mineral density, bioelectrical impedance analysis, handgrip strength, and gait speed was investigated. In women, we found increased thoracic kyphosis in the 60s and pelvic retroversion in the 70s. In men, slight changes in local sagittal alignment were observed with age. Multiple linear regression analyses revealed that sagittal balance was associated with both age and vertebral fractures in men but only with age in women. Age-related changes in spinopelvic sagittal alignment differed between men and women, with men exhibiting nonstructural changes and women experiencing structural changes. In men, both age and vertebral fracture contributed to sagittal imbalance, whereas in women, only aging was associated with sagittal imbalance.

Indexed as

Postural BalanceSex FactorsSpineAdultAgedAged, 80 and overBone DensityCross-Sectional StudiesEast Asian PeopleFemaleHand StrengthHumansJapanKyphosisMaleMiddle AgedAge-related changeCross-sectional studySagittal alignmentSagittal balanceSex differences

Identifiers

PMID40404836
PMCPMC12099002

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.