Evidence map›Paper›PMID 40404824›Full record

ArticlePediatric research2026

Neurodevelopment of children born with gastroschisis: a scoping review.

Bianca de Moraes Rego Martins, Nathalia Cristina Oliveira de Souza, Maria Dalva Barbosa Baker Méio, Fernanda Rebelo, Carla Trevisan Martins Ribeiro

Abstract readScoping Review
PubMed Publisher
In one paragraph

Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Smart assistive technologies for neurodisorders: A review on AI, IoT, and wearable systems for enhanced patient care.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bianca de Moraes Rego MartinsDepartment of Surgery, Surgical NICU, Instituto Fernandes Figueira - Fundação Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil. martinsbianca@hotmail.com.
Nathalia Cristina Oliveira de SouzaDepartment of Neurofunctional Physiotherapy, Surgical NICU, Instituto Fernandes Figueira - Fundação Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil.
Maria Dalva Barbosa Baker MéioClinical Research Unit, Instituto Fernandes Figueira - Fundação Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil.
Fernanda RebeloClinical Research Unit, Instituto Fernandes Figueira - Fundação Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil.
Carla Trevisan Martins RibeiroDepartment of Neurofunctional Physiotherapy, Surgical NICU, Instituto Fernandes Figueira - Fundação Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neurodevelopment of children with gastroschisis may be affected by intrinsic (exposure of the abdominal viscera to the amniotic fluid, causing an inflammatory reaction) and extrinsic (pain, mobility restriction, hospitalization) factors. Thus, the objective of this study was to analyze the information available in the literature on the neurodevelopment of children born with this pathology. A scoping review was done, considering as outcomes the neurodevelopment in the motor, cognitive and language domains. A search was performed in the main databases using the term "gastroschisis", associated with: "neurodevelopment", "impairment", "motor delay" and "language delay". Articles in English, published in the last 10 years, were included; but those that addressed other pathologies were excluded. Eleven studies were included, mostly case series (n = 7), with samples ranging from 14 to 88 participants and ages ranging from 12 months to 10 years. The results were controversial, some reporting normal development, and others reporting deficiencies in all domains. Complex gastroschisis can be an additional risk for neurodevelopment delays. Gastroschisis is a relatively rare malformation, but the increased survival of these children stresses the relevance of investigating short- and long-term outcomes in relation to neurodevelopment to improve the care of this population. IMPACT: This review provides a comprehensive update on neurodevelopment of children born with gastroschisis. There is insufficient evidence to support or reject the idea that gastroschisis interferes negatively with neurodevelopment, but complex gastroschisis can be an additional risk for neurodevelopment delays in this population. Prematurity and being born small-for-gestation-age are confounders factors on evaluation of neurodevelopment on children born with gastroschisis. Additional studies to obtain sufficient information size, focusing on lowering bias risk, and with longer duration of analysis, are required.

Indexed as

Child DevelopmentDevelopmental DisabilitiesGastroschisisNeurodevelopmental DisordersAdolescentChildChild, PreschoolCognitionHumansInfantInfant, Newborn

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.