Evidence map›Paper›PMID 40404691›Full record

ArticleScientific reports2025

Association between cardiometabolic index and abdominal aortic calcification in US adults from the NHANES.

Minjiang Ren, Yifan Shen, Ye Yuan, Zhiyu Han, Yun Zhong, Shiming Liu

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Minjiang RenDepartment of Cardiology, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510260, Guangdong, China.
Yifan ShenDepartment of Cardiology, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510260, Guangdong, China.
Ye YuanDepartment of Cardiology, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510260, Guangdong, China.
Zhiyu HanDepartment of Cardiology, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510260, Guangdong, China.
Yun ZhongDepartment of Cardiology, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510260, Guangdong, China. zhongyun@gzhmu.edu.cn.
Shiming LiuDepartment of Cardiology, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510260, Guangdong, China. gzliushiming@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abdominal aortic calcification (AAC) and atherosclerosis are prevalent conditions among older adults, and recent research suggests that their association may extend beyond the effects of aging alone. An essential instrument for determining the possibility of cardiovascular disease (CVD) is the cardiometabolic index (CMI), a new lipid-based index sensitive to visceral obesity. However, little has been established about the relationship between CMI and AAC. We examined CMI and AAC data from the National Health and Nutrition Examination Survey (NHANES) conducted in 2013-2014 for this study. The relationship between AAC, severe abdominal aortic calcification (SAAC), and CMI was assessed using multiple linear and logistic regression models. The overall trend was visualized using smoothed curve modeling. Subgroup analyses were conducted to find possible moderating factors. Among the 2704 participants included, those with higher CMI levels exhibited much greater AAC scores and a higher prevalence of SAAC. In model 3, elevated CMI positively correlated with AAC (0.25 (0.09, 0.41)) and with the odds of SAAC (OR = 1.35 (1.09, 1.67)). Participants in the highest CMI quartile had an AAC score that was 0.65 units higher (β = 0.65 (0.26, 1.04)) and an 114% higher risk of SAAC (OR = 2.14 (1.29, 3.54)). Subgroup analyses indicated sex and smoking status significantly modified the relationship between CMI, AAC, and SAAC, while previously diagnosed with congestive heart failure (CHF) and heart attack significantly moderated the association between CMI and AAC. These results imply that greater AAC scores and a higher risk of SAAC are linked to heightened CMI, which represents visceral fat storage and disturbed lipid metabolism. Our findings indicate that CMI is correlated with AAC in certain demographic and cardiovascular subgroups, suggesting its potential as an exploratory indicator of elevated AAC risk in these populations.

Indexed as

Aorta, AbdominalAortic DiseasesCardiovascular DiseasesVascular CalcificationAdultAgedFemaleHumansMaleMiddle AgedNutrition SurveysPrevalenceRisk FactorsUnited StatesAbdominal aortic calcificationCardiometabolic indexCross-sectional studyNHANES

Identifiers

PMID40404691
PMCPMC12098828

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.