ArticleNature communications2025
Bioresorbable, wireless dual stimulator for peripheral nerve regeneration.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Bioresorbable and optically readable triboelectric implants enabled by nanoscale iridophosphors.Nature nanotechnology · 2026Article
- Materials-Structure-Hardware-Algorithm Co-Driven Hierarchical Optimization for Flexible Sensors.Nano-micro letters · 2026Review
- Multiscale biomimetic design for peripheral nerve repair: Beyond passive bridging.Materials today. Bio · 2026Review
- Neural dynamics of temporal interference stimulation monitoring by soft liquid metal interfaces across neural systems.Nature communications · 2026Article
- Active devices and systems for closed-loop neuromodulation.Microsystems & nanoengineering · 2026Review
- Liquid Metals for Reconfigurable Bioelectronics.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Wireless flexible patch based on ultrasound-responsive SenA@ZIF-8 release for on-demand medication of periodontitis.Journal of nanobiotechnology · 2026Article
- Transforming healthcare through in-body bioelectronic systems.Nature communications · 2026Review
- Peptide concentration gradients and aligned microfiber topography synergize to speed and direct Schwann cell migration.Acta biomaterialia · 2026Article
- Dissolution Study of Biodegradable Magnesium Silicide Thin Films for Transient Electronic Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Scaling beyond the vagus nerve: historical and contemporary progress on electrode-based small-diameter peripheral nerve interfaces.Bioelectronic medicine · 2026Review
- Optoelectronic Interfaces for Nongenetic Modulation of Excitable Tissues.Small methods · 2026Review
- A self-wrapping, bioresorbable neural interface for wireless multimodal therapy of localized peripheral nerve injury.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Biodegradable Implantable Electronics with Wireless Technology for Real-Time Clinical Applications.Advanced healthcare materials · 2026Review
- Autonomous Implants.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Enhancing peripheral nerve regeneration with rehabilitation and biomaterial-driven drug delivery strategies.Progress in biomedical engineering (Bristol, England) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
28 authors.
Funding
Abstract
Wireless bioresorbable electrical stimulators have broad potential as therapeutic implants. Such devices operate for a clinically relevant duration and then harmlessly dissolve, eliminating the need for surgical removal. A representative application is in treating peripheral nerve injuries through targeted stimulation at either proximal or distal sites, with operation for up to one week. This report introduces enhanced devices with additional capabilities: (1) simultaneous stimulation of both proximal and distal sites, and (2) robust operation for as long as several months, all achieved with materials that naturally resorb by hydrolysis in surrounding biofluids. Systematic investigations of the materials and design aspects highlight the key features that enable dual stimulation and with enhanced stability. Animal model studies illustrate beneficial effects in promoting peripheral nerve regeneration, as quantified by increased total muscle and muscle fiber cross-sectional area and compound muscle action potentials. These findings expand the clinical applications of bioresorbable stimulators, particularly for long-term nerve regeneration and continuous neuromodulation-based monitoring.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.