Evidence map›Paper›PMID 40404646›Full record

ArticleScientific data2025

A near telomere-to-telomere phased reference assembly for the male mountain gorilla.

David R Nelson, Richard Muvunyi, Khaled M Hazzouri, Jean-Claude Tumushime, Gaspard Nzayisenga, Nziza Julius, Wim Meert, Latifa Karim, Wouter Coppieters, Katherine M Munson and 4 more

Abstract readDataset
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

David R NelsonLaboratory of Algal, Synthetic, and Systems Biology, Division of Science and Math, New York University Abu Dhabi (NYUAD), Abu Dhabi, UAE. drn2@nyu.edu.ORCID http://orcid.org/0000-0001-8868-5734
Richard MuvunyiViral Interactomes Laboratory, GIGA Institute, University of Liege, Liege, Belgium.
Khaled M HazzouriKhalifa Center for Genetic Engineering & Biotechnology (KCGEB/UAEU), United Arab Emirates University, Al Ain, Abu Dhabi, UAE.
Jean-Claude TumushimeViral Interactomes Laboratory, GIGA Institute, University of Liege, Liege, Belgium.
Gaspard NzayisengaMountain Gorilla Veterinary Project, "Gorilla Doctors", Musanze, Rwanda.
Nziza JuliusMountain Gorilla Veterinary Project, "Gorilla Doctors", Musanze, Rwanda.
Wim MeertGenomics Core Leuven, Center for Human Genetics, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0001-8019-4893
Latifa KarimGenomics Platform, GIGA Institute, University of Liege, Liege, Belgium.
Wouter CoppietersGenomics Platform, GIGA Institute, University of Liege, Liege, Belgium.
Katherine M MunsonDepartment of Genome Sciences, University of Washington School of Medicine, Seattle, Washington, USA.ORCID http://orcid.org/0000-0001-8413-6498
DongAhn YooDepartment of Genome Sciences, University of Washington School of Medicine, Seattle, Washington, USA.
Evan E EichlerDepartment of Genome Sciences, University of Washington School of Medicine, Seattle, Washington, USA.ORCID http://orcid.org/0000-0002-8246-4014
Kourosh Salehi-AshtianiLaboratory of Algal, Synthetic, and Systems Biology, Division of Science and Math, New York University Abu Dhabi (NYUAD), Abu Dhabi, UAE. ksa3@nyu.edu.
Jean-Claude TwizereLaboratory of Algal, Synthetic, and Systems Biology, Division of Science and Math, New York University Abu Dhabi (NYUAD), Abu Dhabi, UAE. jean-claude.twizere@uliege.be.ORCID http://orcid.org/0000-0002-8683-705X

Funding

Sequence and Assembly of Segmental DuplicationsR01HG002385 · NHGRI · UNIVERSITY OF WASHINGTON · PI Evan Eichler · 2001 to 2026
$13.3M
NHGRI NIH HHS R01 HG002385
6 · The paper itself

Abstract

The endangered mountain gorilla, Gorilla beringei beringei, faces numerous threats to its survival, highlighting the urgent need for genomic resources to aid conservation efforts. Here, we present a near telomere-to-telomere, haplotype-phased reference genome assembly for a male mountain gorilla generated using PacBio HiFi (26.77× ave. coverage) and Oxford Nanopore Technologies (52.87× ave. coverage) data. The resulting non-scaffolded assembly exhibits exceptional contiguity, with contig N50 of ~95 Mbp for the combined pseudohaplotype (3,540,458,497 bp), 56.5 Mbp (3.1 Gbp) and 51.0 Mbp (3.2 Gbp) for each haplotype, an average QV of 65.15 (error rate = 3.1 × 10

Indexed as

GenomeGorilla gorillaTelomereAnimalsEndangered SpeciesHaplotypesMale

Identifiers

PMID40404646
PMCPMC12098815

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.