Evidence map›Paper›PMID 40404621›Full record

ArticleNature communications2025

Selection of self-assembled configurational isomers from a dynamic library via a multivariant optimization process.

Hongye Chen, Tsukasa Abe, Runyu Chai, Shuichi Hiraoka

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hongye ChenDepartment of Basic Science, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan.
Tsukasa AbeDepartment of Basic Science, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0002-2400-3797
Runyu ChaiDepartment of Basic Science, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan.ORCID http://orcid.org/0009-0006-2808-6223
Shuichi HiraokaDepartment of Basic Science, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan. hiraoka-s@g.ecc.u-tokyo.ac.jp.ORCID http://orcid.org/0000-0002-9262-4747

Funding

Asahi Glass Foundation noneMEXT | Japan Society for the Promotion of Science (JSPS) 23H01970
6 · The paper itself

Abstract

Selection of a suitable species from a dynamic library in response to external stimuli is a key event in evolution, adaptation, and switching. The desymmetrization of building blocks enables the generation of configurational isomers for self-assembly, which is a rational approach to creating a complicated dynamic library without increasing the variety of components. However, because of their structural similarity, the selection of isomers from such a dynamic library is challenging. Here we show an artificial molecular system in which two types of self-assemblies are separately selected from a dynamic library consisting of 16 configurational isomers of hexameric cube-shaped entities assembled from C

Identifiers

PMID40404621
PMCPMC12098918

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.