Evidence map›Paper›PMID 40404614›Full record

ArticleNature communications2025

An mRNA-display derived cyclic peptide scaffold reveals the substrate binding interactions of an N-terminal cysteine oxidase.

Yannasittha Jiramongkol, Karishma Patel, Jason Johansen-Leete, Joshua W C Maxwell, Yiqun Chang, Jonathan J Du, Toby Passioura, Kristina M Cook, Richard J Payne, Mark D White

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Peptide Aptamers: Innovative Design and Applications in Pathogen Detection.Chembiochem : a European journal of chemical biology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yannasittha JiramongkolSchool of Chemistry, The University of Sydney, Sydney, NSW, Australia.ORCID http://orcid.org/0000-0003-1824-4313
Karishma PatelSchool of Chemistry, The University of Sydney, Sydney, NSW, Australia.ORCID http://orcid.org/0000-0003-3034-3840
Jason Johansen-LeeteSchool of Chemistry, The University of Sydney, Sydney, NSW, Australia.
Joshua W C MaxwellSchool of Chemistry, The University of Sydney, Sydney, NSW, Australia.
Yiqun ChangSchool of Pharmacy, The University of Sydney, Sydney, NSW, Australia.
Jonathan J DuSchool of Pharmacy, The University of Sydney, Sydney, NSW, Australia.ORCID http://orcid.org/0000-0002-7750-4413
Toby PassiouraSydney Analytical Core Research Facility, The University of Sydney, Sydney, NSW, Australia.
Kristina M CookFaculty of Medicine and Health, Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.ORCID http://orcid.org/0000-0002-0503-7166
Richard J PayneSchool of Chemistry, The University of Sydney, Sydney, NSW, Australia.ORCID http://orcid.org/0000-0002-3618-9226
Mark D WhiteSchool of Chemistry, The University of Sydney, Sydney, NSW, Australia. mark.white@sydney.edu.au.ORCID http://orcid.org/0000-0002-1431-0339

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N-terminal cysteine oxidases (NCOs) act as enzymatic oxygen (O

Indexed as

Cysteine DioxygenasePeptides, CyclicRNA, MessengerAnimalsCatalytic DomainCrystallography, X-RayHumansModels, MolecularOxygenProtein BindingSubstrate SpecificityCysteine DioxygenaseOxygenPeptides, CyclicRNA, Messenger

Identifiers

PMID40404614
PMCPMC12098869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.