Evidence map›Paper›PMID 40404498›Full record

ArticleBritish journal of anaesthesia2026

Depression in older surgical patients: a multicentre prospective longitudinal study.

Yasmin Alhamdah, Ellene Yan, Nina Butris, Paras Kapoor, Leif Erik Lovblom, Tarek K Rajji, Corinne E Fischer, Linda Mah, Jean Wong, Sazzadul Islam and 3 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in British journal of anaesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
  2. Article
  3. Observational
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yasmin AlhamdahDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, Toronto, ON, Canada; Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, ON, Canada.
Ellene YanDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, Toronto, ON, Canada; Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, ON, Canada.
Nina ButrisDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, Toronto, ON, Canada; Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, ON, Canada.
Paras KapoorDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, Toronto, ON, Canada; Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, ON, Canada.
Leif Erik LovblomBiostatistics Department, University Health Network, Toronto, ON, Canada.
Tarek K RajjiInstitute of Medical Science, Temerty Faculty of Medicine, University of Toronto, ON, Canada; Department of Psychiatry, Center for Addiction & Mental Health, University of Toronto, Toronto, ON, Canada.
Corinne E FischerInstitute of Medical Science, Temerty Faculty of Medicine, University of Toronto, ON, Canada; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, ON, Canada.
Linda MahInstitute of Medical Science, Temerty Faculty of Medicine, University of Toronto, ON, Canada; Rotman Research Institute, Baycrest Health Sciences Centre, Toronto, ON, Canada.
Jean WongDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, Toronto, ON, Canada; Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, ON, Canada.
Sazzadul IslamDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, Toronto, ON, Canada.
Aparna SaripellaDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, Toronto, ON, Canada.
David HeDepartment of Anesthesiology and Pain Medicine, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.
Frances ChungDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, Toronto, ON, Canada; Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, ON, Canada. Electronic address: frances.chung@uhn.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA longitudinal examination of postoperative depression is important for risk assessment. We aimed to explore the prevalence and trajectory of depression in older surgical patients, before surgery, and at 30, 90, and 180 days after surgery, associated risk factors, and clinical outcomes.

methodsThis prospective cohort study assessed 307 male and female surgical patients aged ≥65 yr in two preoperative clinics in Canada. All participants completed an online survey before and after surgery that contained the 15-item Geriatric Depression Scale with a ≥5 cut-off to define depression. We also assessed risk factors and clinical and patient-centred outcomes associated with depression.

resultsPreoperative depression was present in 20.2% (95% confidence interval [CI]: 16.1-25.1) of participants and 17.6% had potentially unrecognised depression. Overall, 18.7% (95% CI: 14.1-24.3) reported depression at 180 days after surgery. Participants with preoperative cognitive impairment (odds ratio [OR]: 2.91, 95% CI: 1.29-6.61, P=0.010) and sleep disturbances (OR: 2.91, 95% CI: 1.29-7.07, P=0.013) each had three-fold higher odds of preoperative depression. Those with preoperative functional disability had four-fold higher odds of preoperative depression (OR: 4.15, 95% CI: 1.58-11.54, P=0.005) and six-fold higher odds of depression at 180 days after surgery (OR: 5.91, 95% CI: 1.43-29.07, P=0.019). The depression group had 2.5-fold higher odds for non-home discharge (OR: 2.40, 95% CI: 1.08-5.10, P=0.026).

conclusionsThe prevalence of depression was 20.2% before surgery and 18.7% at 180 days after surgery. Our findings highlight the interconnectedness of mental health with factors such as function, cognition, and sleep.

Indexed as

DepressionPostoperative ComplicationsAgedAged, 80 and overCanadaFemaleGeriatric AssessmentHumansLongitudinal StudiesMalePrevalenceProspective StudiesRisk Factorsclinical outcomesdepressionGeriatric Depression Scaleolder patientsperioperative caresurgical recovery

Identifiers

PMID40404498
PMCPMC13494204

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.