Evidence map›Paper›PMID 40404212›Full record

ArticleThe European respiratory journal2025

How do people with COPD walk? A European study on digitally measured real-world gait.

Laura Delgado-Ortiz, Joren Buekers, Nikolaos Chynkiamis, Heleen Demeyer, Anja Frei, Elena Gimeno-Santos, Clint Hansen, Jeffrey M Hausdorff, Nicholas S Hopkinson, Carl-Philipp Jansen and 14 more

Abstract readMulticenter Study
In one paragraph

Article in The European respiratory journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors.

Laura Delgado-OrtizISGlobal, Barcelona, Spain.ORCID https://orcid.org/0000-0003-0311-7661
Joren BuekersISGlobal, Barcelona, Spain.ORCID https://orcid.org/0000-0003-4866-5741
Nikolaos ChynkiamisThorax Research Foundation, Athens, Greece.ORCID https://orcid.org/0000-0002-9595-6974
Heleen DemeyerKU Leuven, Department of Rehabilitation Sciences, Leuven, Belgium.
Anja FreiEpidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-7134-1000
Elena Gimeno-SantosISGlobal, Barcelona, Spain.
Clint HansenKiel University, Kiel, Germany.
Jeffrey M HausdorffCenter for the Study of Movement, Cognition, and Mobility, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Nicholas S HopkinsonNational Heart and Lung Institute, Imperial College London, London, UK.ORCID https://orcid.org/0000-0003-3235-0454
Carl-Philipp JansenRobert Bosch Gesellschaft für Medizinische Forschung, Stuttgart, Germany.
Anne KirstenVelocity Clinical Research Ahrensburg, formerly Pulmonary Research Institute at LungenClinic Grosshansdorf, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Ahrensburg, Germany.
Sarah KochISGlobal, Barcelona, Spain.
Walter MaetzlerKiel University, Kiel, Germany.ORCID https://orcid.org/0000-0002-5945-4694
Dimitrios MegaritisDepartment of Sport, Exercise and Rehabilitation, Northumbria University Newcastle, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0001-6786-4346
Milo A PuhanEpidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0003-4721-1879
David SingletonUniversity College Dublin, Dublin, Ireland.
Ioannis VogiatzisDepartment of Sport, Exercise and Rehabilitation, Northumbria University Newcastle, Newcastle upon Tyne, UK.
Henrik WatzVelocity Clinical Research Ahrensburg, formerly Pulmonary Research Institute at LungenClinic Grosshansdorf, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Ahrensburg, Germany.
Silvia Del DinTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0003-1154-4751
Brian CaulfieldUniversity College Dublin, Dublin, Ireland.
Clemens BeckerRobert Bosch Gesellschaft für Medizinische Forschung, Stuttgart, Germany.
Lynn RochesterTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0001-5774-9272
Thierry TroostersKU Leuven, Department of Rehabilitation Sciences, Leuven, Belgium.
Judith Garcia-AymerichISGlobal, Barcelona, Spain judith.garcia@isglobal.org.ORCID https://orcid.org/0000-0002-7097-4586

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe

methods549 people with COPD from seven European sites and 19 healthy older adults wore single wearable devices (either Axivity AX6 or DynaPort MoveMonitor MM+) continuously for 1 week, from which we identified walking bouts, calculated 15 digital mobility outcomes (DMOs) aggregated at the weekly level, and compared them across COPD severity levels and with healthy peers.

resultsOf the participants with COPD, 37% were female with a mean±sd age of 68±8 years and a post-bronchodilator forced expiratory volume in 1 s of 54±20% predicted. All gait DMOs were normally distributed and exhibited variability between participants (

conclusionIn people with COPD, gait DMOs are normally distributed and worsen as disease advances. Moreover, walking speed and cadence DMOs are significantly altered when compared to healthy peers. Further research should elucidate which DMOs can be improved with treatments to enhance mobility and reduce adverse events.

Indexed as

GaitPulmonary Disease, Chronic ObstructiveWalkingAgedCase-Control StudiesEuropeFemaleForced Expiratory VolumeHumansMaleMiddle AgedSeverity of Illness IndexWalking SpeedWearable Electronic Devices

Identifiers

PMID40404212
PMCPMC12287607

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.