Evidence map›Paper›PMID 40404026›Full record

ArticleJournal of vascular surgery2025

Implementation of enhanced recovery pathway for lower extremity arterial bypass decreases length of stay.

Calvin L Chao, Lara Lopes, Nidhi K Reddy, Deena El-Gabri, Lauren A Broucek, Rebekkah B Sobolewski, Nicole Willens, Kyle W Prochno, Eric B Pillado, Joseph R Schneider and 4 more

Abstract read
In one paragraph

Article in Journal of vascular surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Calvin L ChaoDivision of Vascular Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.
Lara LopesDivision of Vascular Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.
Nidhi K ReddyDivision of Vascular Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.
Deena El-GabriDivision of Vascular Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.
Lauren A BroucekDivision of Vascular Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.
Rebekkah B SobolewskiDivision of Vascular Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.
Nicole WillensQuality Department, Northwestern Memorial Hospital, Chicago, IL.
Kyle W ProchnoDivision of Vascular Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.
Eric B PilladoDivision of Vascular Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.
Joseph R SchneiderDivision of Vascular Surgery, Northwestern Medicine, Winfield, IL.
Julia B WilkinsonDivision of Vascular Surgery, Northwestern Medicine, Winfield, IL.
Andrew W HoelDivision of Vascular Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.
Tadaki M TomitaDivision of Vascular Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.
Ashley K VavraDivision of Vascular Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL. Electronic address: ashley.vavra@nm.org.

Funding

Vascular Surgery Scientist Training ProgramT32HL094293 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ESKANDARI, MARK K · 2009 to 2023
$4.0M
NHLBI NIH HHS T32 HL094293
6 · The paper itself

Abstract

objectiveFrailty, nutrition, and comorbid conditions are all challenges that contribute to significant morbidity in patients undergoing lower extremity arterial bypass (LEAB). Evidence supports that enhanced recovery pathways (erps) can improve perioperative outcomes. However, few studies have demonstrated successful implementation of an ERP for LEAB. The goal of this study was to demonstrate the successful implementation of an ERP in a complex patient population undergoing LEAB, including elective, urgent, or emergent procedures with the goal of decreasing length of stay (LOS) and morbidity for patients undergoing these procedures at our institution.

methodsMultistakeholder meetings with representatives from all vascular surgery practice sites in the Northwestern Medicine system were conducted to review current evidence-based practices and finalize an ERP for patients undergoing LEAB. Pathway elements included standardized patient education, minimal perioperative fasting with preoperative carbohydrate loading, opioid-sparing analgesia, and early postoperative diet and mobilization. The ERP was initiated in February 2022 as a pilot at a single institution. At 20 months, patient data and process and outcome measures were abstracted from the medical record and validated by four independent reviewers for univariate analysis.

resultsOver the 20-month study period, 112 patients underwent LEAB. Process measures were tracked to determine compliance with the ERP. Patients had to receive >70% of the pathway elements to be considered part of the ERP (n = 60). If patients missed >30% of the elements, they were analyzed as traditional pathway (n = 52). There were no significant differences in patient demographics, body mass index, or hemoglobin a1c. ERP patients were more likely to be elective (76.7% vs 48.1%; P = .0004) and for chronic limb-threatening ischemia (76.7% vs 48.1%; P = .001) and less likely to be urgent or emergent. No significant difference was observed in frequency of infrageniculate bypass target or operative duration. Compliance with 10 perioperative process measures ranged from 28% to 98% in the ERP group. Compliance was most successful with preoperative education (81.6%), chlorhexidine wash (80.0%), postoperative mobilization (90.0%), early solid diet (98.3%), and postoperative opioid sparing strategies (98.3%). Challenges included preoperative acetaminophen (28.3%), carbohydrate load (33.8%), and postoperative protein supplementation (28.3%). Notably, ERP patients demonstrated significantly reduced total LOS (7.8 days vs 13.6 days; P = .014), postoperative LOS (6.0 days vs 11.0 days; P = .0058), and unplanned reoperations (10.0% vs 28.9%; P = .015) when compared with traditional pathway patients. ERP patients trended toward fewer unplanned readmissions (13.3% vs 26.9%; P = .095).

conclusionsOur findings suggest that an ERP for LEAB is feasible in both elective and nonelective settings, although compliance with the ERP individual elements was more challenging for patients undergoing procedures for emergent or urgent indications. Patients undergoing ERP had improved compliance with process measures, reduced LOS, and fewer unplanned reoperations. Our results highlight the benefits of ERP for LEAB and the complex vascular surgery population and some of the potential barriers worth considering in this patient population.

Indexed as

Critical PathwaysEnhanced Recovery After SurgeryLength of StayLower ExtremityPeripheral Arterial DiseaseVascular GraftingAgedAged, 80 and overFemaleHumansMaleMiddle AgedPilot ProjectsPostoperative ComplicationsRecovery of FunctionRetrospective StudiesEnhanced recovery programLength of stayLower extremity bypassPeripheral arterial diseaseQuality improvement

Identifiers

PMID40404026
PMCPMC12955375

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.