Evidence map›Paper›PMID 40403877›Full record

ReviewMolecules and cells2025

A novel high-throughput single-molecule technique DNA curtain: Applications for DNA metabolism.

Soyeong An, Youngseo Kim, Ja Yil Lee

Abstract readReview
In one paragraph

Review in Molecules and cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Soyeong AnDepartment of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
Youngseo KimDepartment of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
Ja Yil LeeDepartment of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea; Institute of Basic Science Center for Genomic Integrity, Ulsan 44919, Republic of Korea. Electronic address: biojayil@unist.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The advancement of single-molecule imaging techniques has significantly enhanced our understanding of biomolecular reactions and cellular processes that remain obscured in ensemble measurements. In particular, DNA curtains are high-throughput hybrid methods integrating total internal reflection fluorescence microscopy, lipid fluidity, microfluidics, and nano-fabrication, enabling the direct visualization of protein-DNA interactions in real time. The techniques have emerged as powerful tools for probing molecular dynamics of diverse DNA metabolic processes, including DNA damage repair and chromatin dynamics. This review not only highlights recent applications of DNA curtain techniques for elucidating mechanisms underlying DNA damage repair and chromatin dynamics, but also shows how DNA curtain techniques have provided novel insights into the interplay between DNA metabolic processes in the chromatin context.

Indexed as

DNASingle Molecule ImagingAnimalsChromatinDNA DamageDNA RepairHigh-Throughput Screening AssaysHumansMicroscopy, FluorescenceChromatinDNAChromatin dynamicsDNA curtainsDNA damage repairSingle-molecule imaging

Identifiers

PMID40403877
PMCPMC12175710

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.