Evidence map›Paper›PMID 40403740›Full record

ArticleJapanese journal of clinical oncology2025

Protocol digest of a single-arm confirmatory trial for less intensive postoperative surveillance in low-risk colorectal cancer patients: JCOG1915 (less study).

Yuta Sekino, Konosuke Moritani, Junki Mizusawa, Dai Shida, Tsukamoto Shunsuke, Tetsuya Hamaguchi, Atsuo Takashima, Akio Shiomi, Masaaki Ito, Yuichi Takayama and 10 more

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Japanese journal of clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Yuta SekinoJapan Clinical Oncology Group Data Center/Operations Office, National Cancer Center Hospital, Tokyo, Japan.
Konosuke MoritaniDepartment of Colorectal Surgery, National Cancer Center Hospital, Tokyo 104-0045, Japan.
Junki MizusawaJapan Clinical Oncology Group Data Center/Operations Office, National Cancer Center Hospital, Tokyo, Japan.
Dai ShidaDivision of Frontier Surgery, Institute of Medical Science, The University of Tokyo 113-8655, Tokyo, Japan.
Tsukamoto ShunsukeDepartment of Colorectal Surgery, National Cancer Center Hospital, Tokyo 104-0045, Japan.
Tetsuya HamaguchiDepartment of Gastroenterology, Saitama Medical University International Medical Center, Hidaka, Saitama 350-1298, Japan.
Atsuo TakashimaGastrointestinal Medical Oncology Division, National Cancer Center Hospital, Tokyo 104-0045, Japan.
Akio ShiomiDivision of Colon and Rectal Surgery, Shizuoka Cancer Center Hospital, Shizuoka 411-8777, Japan.
Masaaki ItoDepartment of Colorectal Surgery, National Cancer Center Hospital East, Kashiwanoha, Kashiwa, Chiba 277-8577, Japan.
Yuichi TakayamaDepartment of Surgery, Ogaki Municipal Hospital, Ogaki, Gifu 503-8502, Japan.
Makoto KinouchiDepartment of Surgery, Miyagi Cancer Center, Natori, Miyagi 981-1293, Japan.
Shin FujitaDepartment of Surgery, Tochigi Cancer Center, Utsunomiya, Tochigi 320-0834, Japan.
Manabu ShiozawaDivision of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Kanagawa 241-8515, Japan.
Hideki UenoDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-8513, Japan.
Satoshi IkedaDepartment of Gastroenterological Surgery, Hiroshima Prefectural Hospital, Hiroshima, Hiroshima 734-8530, Japan.
Yasumasa TakiiDepartment of Gastroenterological Surgery, Niigata Cancer Center Hospital, Niigata, Niigata 951-8133, Japan.
Yusuke SanoJapan Clinical Oncology Group Data Center/Operations Office, National Cancer Center Hospital, Tokyo, Japan.
Tomoko KataokaJapan Clinical Oncology Group Data Center/Operations Office, National Cancer Center Hospital, Tokyo, Japan.
Haruhiko FukudaJapan Clinical Oncology Group Data Center/Operations Office, National Cancer Center Hospital, Tokyo, Japan.
Yukihide KanemitsuDepartment of Colorectal Surgery, National Cancer Center Hospital, Tokyo 104-0045, Japan.

Funding

AMED JP23ck0106896National Cancer Center Research and Development Funds 2023-J-03
6 · The paper itself

Abstract

The Japanese Society for Cancer of the Colon and Rectum guidelines recommend intensive surveillance for curatively resected pathological stage I-III colorectal cancer. However, there is still no global consensus on the optimal method, duration, or frequency of surveillance, and no clinical trials have demonstrated the usefulness of surveillance. We are conducting a clinical trial to confirm the efficacy of less-intensive surveillance after R0 resection with lymph node dissection for stage I or low-risk stage II colorectal cancer in patients without risk factors for recurrence. If this less intensive surveillance method proves effective, medical costs will be considerably reduced. The primary endpoint is overall survival. A total of 680 patients will be enrolled from 59 institutions over 2 years. This trial has been registered at the Japan Registry of Clinical Trials (jRCT) as study number jRCT1030220350.

Indexed as

Colorectal NeoplasmsFemaleHumansJapanMaleMiddle AgedRisk Factorscolorectal cancerhealth economicsless intensive surveillance

Identifiers

PMID40403740
PMCPMC12319228

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.