Evidence map›Paper›PMID 40403650›Full record

ArticleJournal of chromatography. A2025

Effects of packing density and adsorption conditions on extracellular vesicle dynamic binding capacities for capillary-channeled polymer (C-CP) fiber columns.

Md Khalid Bin Islam, R Kenneth Marcus

Abstract read
In one paragraph

Article in Journal of chromatography. A, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Md Khalid Bin IslamDepartment of Chemistry, Biosystems Research Complex, Clemson University, Clemson, SC 29634-0973, USA.
R Kenneth MarcusDepartment of Chemistry, Biosystems Research Complex, Clemson University, Clemson, SC 29634-0973, USA. Electronic address: marcusr@clemson.edu.

Funding

Capillary-channeled polymers fibers and films - A platform technology for exosome isolation and analyticsR01GM141347 · NIGMS · CLEMSON UNIVERSITY · PI MARCUS, RICHARD KENNETH · 2022 to 2025
$1.7M
NIGMS NIH HHS R01 GM141347
6 · The paper itself

Abstract

Extracellular vesicles (EVs) are membrane-bound nanoparticles (50-1000 nm) secreted by all cell types and play critical roles in various biological processes. Among these, exosomes, a smaller subset of EVs, have attracted considerable interest due to their potential applications in diagnostics and therapeutics. However, conventional EV isolation methods are often limited by inefficiencies in processing time, recovery, and scalability. Hydrophobic interaction chromatography utilizing capillary-channeled polymer (CCP) fiber stationary phases offers a promising alternative, enabling rapid (<15 min), cost-effective (∼$5 per column) EV isolation with high loading capacities (∼10

Indexed as

Extracellular VesiclesPolymersAdsorptionChromatography, High Pressure LiquidHumansHydrophobic and Hydrophilic InteractionsPolyestersPolyestersPolymersCapillary-channeled polymer fibersDynamic binding capacityExosomesExtracellular vesiclesHigh-performance liquid chromatography

Identifiers

PMID40403650
PMCPMC13197819

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.