Evidence map›Paper›PMID 40402846›Full record

ArticleeLife2025

T-follicular helper cell profiles differ by malaria antigen and for children compared to adults.

Catherine Suzanne Forconi, Christina Nixon, Hannah W Wu, Boaz Odwar, Sunthorn Pond-Tor, John M Ong'echa, Jonathan D Kurtis, Ann M Moormann

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Catherine Suzanne ForconiDivision of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, United States.ORCID https://orcid.org/0000-0001-7358-5546
Christina NixonDepartment of Pathology and Laboratory Medicine, Brown University, Providence, United States.
Hannah W WuDepartment of Pathology and Laboratory Medicine, Brown University, Providence, United States.
Boaz OdwarCenter for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
Sunthorn Pond-TorDepartment of Pathology and Laboratory Medicine, Brown University, Providence, United States.
John M Ong'echaCenter for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.ORCID https://orcid.org/0000-0003-3928-6774
Jonathan D KurtisDepartment of Pathology and Laboratory Medicine, Brown University, Providence, United States.ORCID https://orcid.org/0000-0003-1032-9558
Ann M MoormannDivision of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, United States.ORCID https://orcid.org/0000-0003-1113-2829

Funding

Tfh responses to novel vaccine candidates and protection from pediatric falciparum malariaR01AI127699 · NIAID · BROWN UNIVERSITY · PI KURTIS, JONATHAN D. · 2017 to 2021
$3.4M
NIAID NIH HHS R01 AI127699NIH HHS R01AI127699-01A1
6 · The paper itself

Abstract

Circulating T-follicular helper (cT

Indexed as

Antigens, ProtozoanMalaria, FalciparumPlasmodium falciparumT Follicular Helper CellsAdolescentAdultAntibodies, ProtozoanChildChild, PreschoolFemaleHumansKenyaMalaria VaccinesMaleYoung AdultAntibodies, ProtozoanAntigens, ProtozoanMalaria VaccinesimmunologyinflammationKenyaP. falciparumpf-malariaT-follicular helpervaccine candidates

Identifiers

PMID40402846
PMCPMC12097790

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.