ArticleInvestigative ophthalmology & visual science2025
Monocular Contrast Sensitivity Visual Perceptual Learning Rebalances Adult Amblyopes' Two Eyes.
Article in Investigative ophthalmology & visual science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Treatment strategies for amblyopia in adults: an overview of conventional methods and new technologies.Romanian journal of ophthalmologyPooled it
- Advances in behavioral vision training for the treatment of childhood amblyopia: a narrative review.Translational pediatrics · 2026Review
- Editorial: Development and neuroplasticity of the visual system, amblyopia and beyond.Frontiers in neuroscience · 2026Article
- Effect of active vision therapy on contrast sensitivity in bilateral amblyopia.International journal of ophthalmology · 2026Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study investigates the effects of monocular contrast sensitivity visual perceptual learning on binocular visual functions of adults with binocular imbalances. Methods: Sixteen adults with anisometropic amblyopia (mean age, 24.63 ± 3.56 years), 20 adults with myopic anisometropia (mean age, 24.20 ± 1.94 years), and 16 visually normal adults (mean age, 24.88 ± 1.89 years) participated in this study. Each group was evenly divided into training (anisometropic amblyopia, myopic anisometropia, normal training group) and untrained control groups (anisometropic amblyopia controls, myopic anisometropia controls, and normal controls). Training groups underwent 10 days of monocular contrast sensitivity perceptual learning (two-alternative forced-choice contrast detection task at 6 cycles per degree) using the amblyopic or nondominant eye, whereas the control groups received no intervention during the same period. Monocular visual acuity, monocular and binocular contrast sensitivity, and balance point were measured before and after the intervention. Results: Monocular contrast sensitivity perceptual learning significantly improved both contrast sensitivity and balance point at the trained spatial frequency (6 cycles per degree) in the trained eyes of the anisometropic amblyopia training group and myopic anisometropia training group, with improvements generalizing to nearby untrained spatial frequencies. However, no significant improvements were observed in binocular summation ratios for either group. The normal training group showed modest improvements limited to the trained eye at both trained and neighboring spatial frequencies, without significant binocular or untrained eye benefits. Conclusions: Monocular contrast sensitivity visual perceptual learning effectively enhances monocular visual performance and positively affects binocular functions across trained and nearby untrained spatial frequencies, indicating its potential clinical usefulness in improving binocular vision among adults with binocular imbalances.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.