ArticleProbiotics and antimicrobial proteins2026
Lactobacillus acidophilus-Derived Cell-Free Supernatant Augments Methylene Blue-Mediated Photodynamic Inactivation Efficacy Against Methicillin Resistant Staphylococcus aureus Planktonic Suspension and Biofilms.
Article in Probiotics and antimicrobial proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Review
- Postbiotics as Multifunctional Bioactives: Mechanistic Insights and Translational Applications in Host Physiology and Microbial Ecosystem Modulation.Microorganisms · 2026Review
- Cell-Free but potent: Antimicrobial potential of Lactobacillus supernatants against multidrug-resistant pathogens.PloS one · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
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Abstract
Infections caused by antimicrobial drug-resistant (AMR) pathogens like methicillin-resistant Staphylococcus aureus (MRSA) have triggered global scale search for innovative, clinically viable and cost affordable alternatives that do not generate resistance. Antimicrobial photodynamic therapy (aPDT) and postbiotics are innovative alternatives to circumvent AMR pathogens. However, MRSA biofilms reduce microbial susceptibility to aPDT and postbiotics. Integrating both modalities can be a novel MRSA anti-biofilm therapeutics avenue, but further studies are needed to validate the efficacy and applicability. We investigated the potentiality of methylene blue (MB)-mediated aPDT (MB-aPDT) followed by Lactobacillus acidophilus-derived cell-free supernatant (LA-CFS) treatment on MRSA planktonic culture, pre-formed biofilms, biofilm initiation, and maturation. Compared to aPDT or LA-CFS monotherapy, MB-aPDT followed by LA-CFS (20 and 40% v/v) treatment for 2 h leads to augmentation in inactivation of MRSA planktonic culture and CFU data correlates with flow cytometry data (R
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.