Evidence map›Paper›PMID 40402414›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2025

Artificial intelligence in neuro-oncology: methodological bases, practical applications and ethical and regulatory issues.

Pedro David Delgado-López, Miguel Cárdenas Montes, Jesús Troya García, Beatriz Ocaña-Tienda, Santiago Cepeda, Ricard Martínez Martínez, Eva María Corrales-García

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pedro David Delgado-LópezServicio de Neurocirugía, Hospital Universitario de Burgos, Avda Islas Baleares 3, 09006, Burgos, Spain. pedrodl@yahoo.com.ORCID http://orcid.org/0000-0002-9317-6958
Miguel Cárdenas MontesDepartamento de Investigación Básica, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), Madrid, Spain.ORCID http://orcid.org/0000-0003-4445-8868
Jesús Troya GarcíaServicio de Medicina Interna, Hospital Universitario Infanta Leonor, Madrid, Spain.ORCID http://orcid.org/0000-0001-7323-114X
Beatriz Ocaña-TiendaCentro Nacional de Investigaciones Oncológicas (CNIO), Unidad de Bioinformática, Madrid, Spain.ORCID http://orcid.org/0000-0001-8931-3836
Santiago CepedaServicio de Neurocirugía, Hospital Universitario Rio Hortega, Valladolid, Spain.ORCID http://orcid.org/0000-0003-1667-8548
Ricard Martínez MartínezFacultad de Derecho, Cátedra de Privacidad y Transformación Digital de la Universidad de Valencia, Valencia, Spain.
Eva María Corrales-GarcíaServicio de Oncología Radioterápica, Hospital Universitario de Burgos, Burgos, Spain.ORCID http://orcid.org/0000-0002-7129-3109

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial Intelligence (AI) is transforming neuro-oncology by enhancing diagnosis, treatment planning, and prognosis prediction. AI-driven approaches-such as CNNs and deep learning-have improved the detection and classification of brain tumors through advanced imaging techniques and genomic analysis. Explainable AI methods mitigate the "black box" problem, promoting model transparency and clinical trust. Mechanistic models complement AI by integrating biological principles, enabling precise tumor growth predictions and treatment response assessments. AI applications also include the creation of digital twins for personalized therapy optimization, virtual clinical trials, and predictive modeling for estimation of tumor resection and pattern of recurrence. However, challenges such as data bias, ethical concerns, and regulatory compliance persist. The European Artificial Intelligence Act and the Health Data Space Regulation impose strict data protection and transparency requirements. This review explores AI's methodological foundations, clinical applications, and ethical challenges in neuro-oncology, emphasizing the need for interdisciplinary collaboration and regulatory adaptation.

Indexed as

Artificial IntelligenceBrain NeoplasmsMedical OncologyDeep LearningHumansArtificial intelligenceDeep learningExplainabilityMachine learningNeural networkNeuro-oncology

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.