Evidence map›Paper›PMID 40402135›Full record

ArticleHealth promotion and chronic disease prevention in Canada : research, policy and practice2025

Prevalence and sequence of chronic conditions in older people with dementia: a multi-province, population-based cohort study.

Susan E Bronskill, Azmina Artani, Laura C Maclagan, Xuesong Wang, Hannah Chung, J Michael Paterson, Andrea Gruneir, Karen A Phillips, Rasaq Ojasanya, Xibiao Ye and 9 more

Abstract read
In one paragraph

Article in Health promotion and chronic disease prevention in Canada : research, policy and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Susan E BronskillICES, Toronto, Ontario, Canada.
Azmina ArtaniICES, Toronto, Ontario, Canada.
Laura C MaclaganICES, Toronto, Ontario, Canada.
Xuesong WangICES, Toronto, Ontario, Canada.
Hannah ChungICES, Toronto, Ontario, Canada.
J Michael PatersonICES, Toronto, Ontario, Canada.
Andrea GruneirDepartment of Family Medicine, Faculty of Medicine and Dentistry, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada.
Karen A PhillipsDepartment of Health and Wellness, Chief Public Health Office, Government of Prince Edward Island, Charlottetown, Prince Edward Island, Canada.
Rasaq OjasanyaDepartment of Health and Wellness, Chief Public Health Office, Government of Prince Edward Island, Charlottetown, Prince Edward Island, Canada.
Xibiao YeOffice of the Provincial Health Officer, Ministry of Health, Victoria, British Columbia, Canada.
Kayla McLeanOffice of the Provincial Health Officer, Ministry of Health, Victoria, British Columbia, Canada.
Fernanda EwerlingOffice of the Provincial Health Officer, Ministry of Health, Victoria, British Columbia, Canada.
Claire Godard-SebillotteDepartment of Medicine and Health Sciences, Division of Geriatrics, McGill University, Montréal, Quebec, Canada.
Victoria MassambaBureau d'information et d'études en santé des populations, Institut national de santé publique du Québec, Québec, Quebec, Canada.
Louis RochetteBureau d'information et d'études en santé des populations, Institut national de santé publique du Québec, Québec, Quebec, Canada.
Isabelle VedelBureau d'information et d'études en santé des populations, Institut national de santé publique du Québec, Québec, Quebec, Canada.
Larry ShaverCentre for Surveillance and Applied Research, Health Promotion and Chronic Disease Prevention Branch, Public Health Agency of Canada, Ottawa, Ontario, Canada.
Catherine PelletierCentre for Surveillance and Applied Research, Health Promotion and Chronic Disease Prevention Branch, Public Health Agency of Canada, Ottawa, Ontario, Canada.
Colleen J MaxwellICES, Toronto, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionComorbid chronic conditions contribute to increased health service use and poor outcomes for people with dementia, but there is little information about the prevalence of these conditions in this population.

methodsWe used linked administrative data from British Columbia (BC), Ontario (ON), Quebec (QC) and Prince Edward Island (PE) to identify a cohort of 287 453 individuals aged 65 years and older with prevalent dementia in April 2015, and followed this population until March 2020. We determined the prevalence of comorbid chronic conditions and ascertainment dates using Canadian Chronic Disease Surveillance System definitions, and used descriptive statistics to compare patterns across provinces.

resultsSociodemographic characteristics were similar across provinces (mean age: 83.0 [PE]-84.3 [BC] years; female sex: 61.8% [BC]-66.2% [QC]; and long-term care facility residence: 39.5% [QC]-41.6% [BC]). People with dementia commonly experienced five or more comorbid conditions (38.8% [PE]-53.5% [ON]); the most prevalent were hypertension (76.4% [PE]-81.4% [ON]), mental illness and alcohol- or druginduced disorders (44.4% [QC]-91.2% [BC]) and osteoarthritis (43.8% [PE]-60.4% [ON]). Hypertension, diabetes and stroke were frequently apparent before dementia ascertainment, whereas heart failure and traumatic brain injury were apparent almost as frequently after dementia ascertainment as before.

conclusionPatterns of comorbid chronic conditions were similar across provinces, with most present prior to dementia ascertainment. Health service planning strategies should be developed and shared across provinces to address the complex health care needs of people with dementia.

Indexed as

DementiaAgedAged, 80 and overCanadaChronic DiseaseCohort StudiesComorbidityFemaleHumansHypertensionMalePrevalencechronic diseasecomorbiditydementiaepidemiologyhypertensionmental illnessosteoarthritispan-Canadian

Identifiers

PMID40402135
PMCPMC12282979

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.