Evidence map›Paper›PMID 40401959›Full record

Observational studyMicrobiology spectrum2025

Bacterial gastroenteritis in the world of culture-independent diagnostic testing: a study to evaluate the kinetics of bacterial shedding by culture and CIDT.

Nathan K McCartney, Surangi H Thilakarathna, Tara Hluchy, Dylan R Pillai, Linda Chui, Byron M Berenger

Abstract readObservational Study
In one paragraph

Observational study in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nathan K McCartneyDepartment of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0009-0002-6680-9884
Surangi H ThilakarathnaDepartment of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada.ORCID 0000-0002-0368-4167
Tara HluchyEnvironmental Public Health, Alberta Health Services, Edmonton, Alberta, Canada.
Dylan R PillaiDepartment of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0001-9518-5551
Linda ChuiDepartment of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada.ORCID 0000-0003-0851-9803
Byron M BerengerDepartment of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0001-9062-6346

Funding

Calgary Laboratory Services
6 · The paper itself

Abstract

Reliable microbiological diagnosis is important for patient and public health management of bacterial gastroenteritis. Clinical laboratories are adopting culture-independent diagnostic tests (CIDT) widely. We examined the kinetics of bacterial shedding by CIDT and culture following an episode of acute gastroenteritis with one of three prevalent pathogens. The primary outcome was the proportion of samples that tested CIDT-positive or culture-positive at defined time intervals after clinical diagnosis. This longitudinal observational study was conducted in Calgary Health Zone (Alberta, Canada) between 2019 and 2022. Eligible adult patients (≥18 years) were consented and enrolled after a routine public health investigation. Stool samples were submitted at weeks 2, 3, 4, 5, and 6 post-diagnosis. Stools were tested using the commercial nucleic acid-based BD MAX Enteric Bacterial Panel (CIDT method) and routine culture methods. Thirty-seven of 83 enrolled individuals (45%) submitted at least one additional stool. Diagnostic specimens were positive for

Indexed as

Bacterial SheddingDiagnostic Tests, RoutineGastroenteritisAdolescentAdultAgedAlbertaBacteriological TechniquesCampylobacterFecesFemaleHumansLongitudinal StudiesMaleMiddle AgedSalmonellabacteriologyCampylobacterculturefecesgastroenteritispolymerase chain reactionSalmonellaShiga toxin-producing Escherichia coli

Identifiers

PMID40401959
PMCPMC12210883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.