Evidence map›Paper›PMID 40401877›Full record

ArticleDermatology practical & conceptual2025

Scabies Management Outcomes: Identification of Risk Factors for Treatment Success or Failure.

Vanessa Azzolina, Franziska Schauer, Julia Felicitas Pilz, Alexander Zink, Kilian Eyerich, Anna Caroline Pilz

Abstract read
In one paragraph

Article in Dermatology practical & conceptual, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Scabies Treatment Failure: Beyond Permethrin and Plastic Bags.Dermatology practical & conceptual · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vanessa AzzolinaDepartment of Dermatology and Venereology, Medical Center, University of Freiburg, Freiburg, Germany.
Franziska SchauerDepartment of Dermatology and Venereology, Medical Center, University of Freiburg, Freiburg, Germany.
Julia Felicitas PilzDepartment of Dermatology and Allergy, Technical University of Munich, School of Medicine and Health, Munich, Germany.
Alexander ZinkDepartment of Dermatology and Allergy, Technical University of Munich, School of Medicine and Health, Munich, Germany.
Kilian EyerichDepartment of Dermatology and Venereology, Medical Center, University of Freiburg, Freiburg, Germany.
Anna Caroline PilzDepartment of Dermatology and Venereology, Medical Center, University of Freiburg, Freiburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionScabies is a parasitic infectious skin disease classified as a neglected tropical disease by the World Health Organization in 2017. Currently, it is becoming a major challenge in high-income countries, with rapidly rising incidence and increasing reports about treatment failure.

objectivesFactors that are associated with treatment failure or success were evaluated.

methodsThis non-interventional prospective observational study was conducted as a questionnaire survey at the Department of Dermatology and Venereology of the University of Freiburg from January to November 2023. Patients that still suffered from scabies 2-6 weeks after medical treatment were classified as "failure"; those who were free of scabies belonged to the success group.

resultsOf 102 participants, with a mean age of 34.4 ± 17.3 years (male: 60.4%), 77 (75.5%) were assigned to the success and 25 (24.5%) to the failure group. A larger proportion of the latter was clinically more severely affected, applied permethrin monotherapy, did not undertake special decontamination measures, but used alcohol as a disinfectant. Treatment success was associated with an additional systemic treatment, a repeated intake of ivermectin, and intensified decontamination measures such as storage of clothes in plastic bags for four days or vacuum cleaning of car seats.

conclusionsOur findings indicate that a consistent second-dose administration of ivermectin and refraining from permethrin monotherapy may be advisable.

Identifiers

PMID40401877
PMCPMC12090963

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.