ArticleDermatology practical & conceptual2025
Psoriasis and Emotional Dysregulation: A Multicenter Analysis of Psychodermatology Outcomes.
Article in Dermatology practical & conceptual, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The brain-gut-skin axis in inflammatory and disfiguring skin diseases: mechanistic insights, clinical correlations, and therapeutic strategies.Frontiers in immunology · 2026Review
- The Skin-Brain Axis in Psoriasis and Depression: Roles of Inflammation, Hormones, Neuroendocrine Pathways, Neuropeptides, and the Microbiome.Psoriasis (Auckland, N.Z.) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPsychological symptoms associated with psoriasis include depression, anxiety, and social phobia, often exacerbated by high rates of alexithymia. Treatment decisions should consider not only clinical severity but also patient characteristics and quality of life. However, the psychosocial burden of psoriasis may not always align with clinical severity.
objectivesThis study aimed to assess emotional regulation difficulties in outpatients with psoriasis, comparing these difficulties to those of the general population and examining associations with sociodemographic factors, comorbidities, and treatment options.
methodsA cross-sectional, multicenter study enrolled 107 consecutive patients with psoriasis from dermatological centers in Lazio, Italy. For every patient the Psoriasis Area Severity Index (PASI), Investigator's Global Assessment (IGA), and Difficulties in Emotional Regulation scale (DERS) were recorded.
resultsAnalysis revealed that patients with psoriasis reported significantly higher emotional regulation difficulties compared to the general Italian population, even those with mild disease. A significant association was found between psoriasis severity and emotional regulation difficulties, particularly in patients with higher PASI scores. Biological treatments were associated with lower levels of emotional regulation difficulties.
conclusionsThis study corroborates the existing literature on the association between psoriasis severity and emotional regulation difficulties. However, it diverges from prior findings regarding the association between body mass index (BMI) and emotional dysregulation. Assessing emotional regulation difficulties may aid clinicians in identifying vulnerable patients and optimizing treatment decisions to improve overall quality of life and treatment adherence. Further research is needed to validate these findings and to explore longitudinal associations between emotional regulation and psoriasis outcomes.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.