ArticleDermatology practical & conceptual2025
Evaluation of Nasal Mucociliary Activity in Patients with Psoriasis Vulgaris.
Article in Dermatology practical & conceptual, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
6 authors.
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Abstract
introductionPsoriasis, a chronic inflammatory dermatological condition, is marked by recurring periods of activity and quiescence. This persistent inflammation contributes to a range of associated health issues. The respiratory system relies on nasal mucociliary clearance as a fundamental defense mechanism. Mucociliary transport dysfunction is frequently observed in chronic inflammatory states.
objectiveWe aimed to determine the relationship between psoriasis and concomitant clinical conditions and nasal mucociliary clearance time (NMCT).
methodWe conducted a study to evaluate NMCTin 34 individuals diagnosed with psoriasis and a control group of 35 healthy individuals.
resultsOur results revealed a statistically significant prolongation of NMCT in the psoriasis group (11.26 ± 2 minutes) compared to the control group (9.2 ± 1.85 minutes, P<0.001). Moreover, a positive correlation was identified between NMCT and both the duration of psoriasis and the Psoriasis Area and Severity Index (PASI). This suggests that impaired nasal mucociliary clearance in individuals with psoriasis, especially those with more severe disease, may elevate their vulnerability to infections of the sinuses and nasal passages.
conclusionThis highlights the need to consider strategies for enhancing mucociliary function in this patient population.
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