Evidence map›Paper›PMID 40401773›Full record

ArticlePhysiologia plantarum

Exploring the Structural Diversity and Evolution of the D1 Subunit of Photosystem II Using AlphaFold and Foldtree.

Tom Dongmin Kim, Daniella Pretorius, James W Murray, Tanai Cardona

Abstract read
In one paragraph

Article in Physiologia plantarum. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Sequence and structural alignments reveal insights into ANKLE2 evolution and function.Protein science : a publication of the Protein Society · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tom Dongmin KimSchool of Biological and Behavioural Sciences, Queen Mary University of London, London, UK.ORCID https://orcid.org/0000-0002-8717-8623
Daniella PretoriusDepartment of Life Sciences, Imperial College London, London, UK.ORCID https://orcid.org/0009-0001-7107-6569
James W MurrayDepartment of Life Sciences, Imperial College London, London, UK.ORCID https://orcid.org/0000-0002-8897-0161
Tanai CardonaSchool of Biological and Behavioural Sciences, Queen Mary University of London, London, UK.ORCID https://orcid.org/0000-0003-2076-4115

Funding

Engineering and Physical Sciences Research Council EP/S022856/1UK Research and Innovation MR/T017546/1UK Research and Innovation MR/T017546/2UK Research and Innovation MR/Y011635/1
6 · The paper itself

Abstract

Although our knowledge of photosystem II has expanded to include time-resolved atomic details, the diversity of experimental structures of the enzyme remains limited. Recent advances in protein structure prediction with AlphaFold offer a promising approach to fill this gap in structural diversity in non-model systems. This study used AlphaFold to predict the structures of the D1 protein, the core subunit of photosystem II, across a broad range of photosynthetic organisms. The prediction produced high-confidence structures, and structural alignment analyses highlighted conserved regions across the different D1 groups, which were in line with high pLDDT scoring regions. In contrast, varying pLDDT in the DE loop and terminal regions appears to correlate with different degrees of structural flexibility or disorder. Subsequent structural phylogenetic analysis using Foldtree provided a tree that is in good agreement with previous sequence-based studies. Moreover, the phylogeny supports a parsimonious scenario in which far-red D1 and D1

Indexed as

Evolution, MolecularPhotosystem II Protein ComplexModels, MolecularPhotosynthesisPhylogenyPhotosystem II Protein ComplexAlphaFoldevolutionphotosystem IIreaction centre protein D1structural prediction

Identifiers

PMID40401773
PMCPMC12096807

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.