Evidence map›Paper›PMID 40401635›Full record

ArticleActa orthopaedica2025

Association of socioeconomic inequality and risk of periprosthetic joint infection after total knee arthroplasty: a Danish cohort study of 75,141 cases.

Marie Anneberg, Anders Troelsen, Per Gundtoft, Alma B Pedersen

Abstract read
In one paragraph

Article in Acta orthopaedica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Machine Learning Based Diagnostic Models for Hip and Knee Prosthetic Joint Infection: A Systematic Review.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marie AnnebergDepartment of Clinical Epidemiology, Aarhus University/Aarhus University Hospital; Department of Orthopedic Surgery, Aalborg University Hospital, Denmark. mab@clin.au.dk.ORCID 0000-0003-2566-8093
Anders TroelsenDepartment of Orthopedic Surgery, Hvidovre Hospital, Denmark.ORCID 0000-0003-0132-8182
Per GundtoftDepartment of Orthopedic Surgery, Aarhus University Hospital, Denmark.ORCID 0000-0002-3688-6865
Alma B PedersenDepartment of Clinical Epidemiology, Aarhus University/Aarhus University Hospital; Department of Clinical Medicine, Aarhus University, Denmark.ORCID 0000-0002-3288-9401

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeAwareness of socioeconomic disparities in outcomes following surgical procedures is increasing. This highlights a critical challenge for clinical practice and public health. We examined whether low socioeconomic position (SEP) was associated with the incidence of revisions due to periprosthetic joint infection (PJI) following total knee arthroplasty (TKA).

methodsThis cohort study included 75,141 patients undergoing TKA (2010-2021), identified from the Danish Knee Arthroplasty Registry (DKR). Individual-level SEP information, including wealth, living arrangements, and education, was obtained from Danish social and administrative registries. Revisions due to PJI were identified using a method combining the DKR and microbiology data. We calculated the cumulative incidence of revision due to PJI at 90 days and 2 years, and 2-year hazard ratios (aHRs) of revision due to PJI for lower vs. higher SEP groups, adjusted for age, sex, weight, and Charlson Comorbidity Index scores, with 95% confidence intervals (CI).

resultsThe incidence of revision due to PJI after 2 years of follow-up was 1.5% (CI 1.3-1.6) for low-wealth patients vs. 1.2% (CI 1.1-1.3) for high-wealth patients (aHR 1.3, CI 1.1-1.5); 1.5% (CI 1.3-1.7) for patients living alone vs. 1.2% (CI 1.1-1.3) for those cohabiting (aHR 1.4, CI 1.2-1.6); and 1.3% (CI 1.1-1.4) for patients with low education vs. 1.2% (CI 1.0-1.4) for those with high education (aHR 1.0, CI 0.8-1.2).

conclusionRevision due to PJI among low-wealth patients and those living alone versus the corresponding high-SEP group were associated with increased risk of revision due to PJI.

Indexed as

Arthroplasty, Replacement, KneeProsthesis-Related InfectionsAgedCohort StudiesDenmarkFemaleHumansIncidenceKnee ProsthesisMaleMiddle AgedRegistriesReoperationRisk FactorsSocioeconomic Factors

Identifiers

PMID40401635
PMCPMC12087143

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