ArticleeLife2025
Subcortical correlates of consciousness with human single neuron recordings.
Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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Who cites it
4 citing papers in PubMed.
- Review
- Conscious Tactile Perception Depends on Early Processing in Primary Somatosensory Cortex.The European journal of neuroscience · 2026Article
- A geometry aware framework enhances noninvasive mapping of whole human brain dynamics.Nature biomedical engineering · 2026Article
- Subcortical contributions to the sense of body ownership.Brain : a journal of neurology · 2024Article
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Authors and funding
11 authors.
Funding
Abstract
Subcortical brain structures such as the subthalamic nucleus or the thalamus are involved in regulating motor and cognitive behavior. However, their contribution to perceptual consciousness remains unclear, due to the inherent difficulties of recording subcortical neuronal activity in humans. Here, we asked neurological patients undergoing surgery for deep brain stimulation to detect weak vibrotactile stimuli applied on their hand while recording single neuron activity from the tip of a microelectrode. We isolated putative single neurons in the subthalamic nucleus and thalamus. A significant proportion of neurons modulated their activity while participants were expecting a stimulus. We found that the firing rate of 23% of these neurons differed between detected and undetected stimuli. Our results provide direct neurophysiological evidence of the involvement of the subthalamic nucleus and the thalamus for the detection of vibrotactile stimuli, thereby calling for a less cortico-centric view of the neural correlates of consciousness.
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Registered trials
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