Evidence map›Paper›PMID 40401616›Full record

ArticleJournal of the American Heart Association2025

Association of Ambient Air Pollution With Invasive Pulmonary Hemodynamics and Long-Term Outcomes in Patients With Pulmonary Arterial Hypertension.

Sicheng Zhang, Luyang Gao, Sicong Li, Manqing Luo, Qunying Xi, Ping Lin, Zhihui Zhao, Qing Zhao, Xiaoxu Xie, Qin Luo and 2 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Particulate matter increases bone morphogenetic protein 2 in lung fibroblasts.American journal of physiology. Lung cellular and molecular physiology · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sicheng ZhangCenter for Respiratory and Pulmonary Vascular Diseases Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Luyang GaoCenter for Respiratory and Pulmonary Vascular Diseases Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.ORCID 0000-0001-8046-8268
Sicong LiCenter for Respiratory and Pulmonary Vascular Diseases Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Manqing LuoDepartment of Cardiology Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University Fujian China.ORCID 0000-0002-5706-1432
Qunying XiCenter for Pulmonary Vascular Diseases Fuwai Hospital, Chinese Academy of Medical Sciences Shenzhen China.
Ping LinDepartment of Pulmonary and Critical Care Medicine The 900 Hospital of the Joint Service Support Force of the People's Liberation Army of China, Fujian Medical University Fuzhou China.
Zhihui ZhaoCenter for Respiratory and Pulmonary Vascular Diseases Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Qing ZhaoCenter for Respiratory and Pulmonary Vascular Diseases Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Xiaoxu XieDepartment of Epidemiology and Health Statistics School of Public Health, Fujian Medical University Fuzhou China.ORCID 0000-0002-3103-3724
Qin LuoCenter for Respiratory and Pulmonary Vascular Diseases Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Yansong GuoDepartment of Cardiology Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University Fujian China.ORCID 0000-0001-6607-6938
Zhihong LiuCenter for Respiratory and Pulmonary Vascular Diseases Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.ORCID 0000-0001-8639-6306

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough the impact of ambient air pollution on mortality in cardiovascular and pulmonary diseases is well documented, its specific link to pulmonary arterial hypertension remains unclear. This study investigated the association between ambient particulate matter (PM) exposure and all-cause death or lung transplantation, as well as pulmonary hemodynamics in patients with pulmonary arterial hypertension.

methodsThis retrospective cohort study included 1327 participants with pulmonary arterial hypertension who underwent right heart catheterization (RHC). Ambient PM

resultsThe median age of the participants was 33.0 years, with 73.2% being women. Median PM

conclusionsLong-term PM

Indexed as

Air PollutionEnvironmental ExposureHemodynamicsParticulate MatterPulmonary Arterial HypertensionAdultCardiac CatheterizationCause of DeathChinaFemaleHumansLung TransplantationMaleMiddle AgedRetrospective StudiesRisk AssessmentParticulate Matterambient air pollutionmediation effectprognosispulmonary arterial hypertensionpulmonary hemodynamics

Identifiers

PMID40401616
PMCPMC12229101

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.