Evidence map›Paper›PMID 40401500›Full record

ArticleJournal of veterinary internal medicine

Association of Lung Consolidation Depth With Pathogens Isolated From Bronchoalveolar Lavage Fluid in Calves With Clinical Signs of Respiratory Disease.

Justine Clinquart, Thomas Lowie, Stan Jourquin, Jade Bokma, Bart Pardon

Abstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Justine ClinquartDepartment of Internal Medicine, Reproduction and Population Medicine, Ghent University, Merelbeke, Belgium.ORCID https://orcid.org/0000-0001-5870-5394
Thomas LowieDepartment of Internal Medicine, Reproduction and Population Medicine, Ghent University, Merelbeke, Belgium.ORCID https://orcid.org/0000-0002-9877-3786
Stan JourquinDepartment of Internal Medicine, Reproduction and Population Medicine, Ghent University, Merelbeke, Belgium.ORCID https://orcid.org/0000-0002-8488-8494
Jade BokmaDepartment of Internal Medicine, Reproduction and Population Medicine, Ghent University, Merelbeke, Belgium.
Bart PardonDepartment of Internal Medicine, Reproduction and Population Medicine, Ghent University, Merelbeke, Belgium.ORCID https://orcid.org/0000-0003-1026-8433

Funding

Bijzonder Onderzoeksfonds UGent BOF/STA/202006/006
6 · The paper itself

Abstract

backgroundThe depth of lung consolidation (≥ 1 and ≥ 3 cm) on thoracic ultrasonography (TUS) is increasingly used as a criterion for antimicrobial treatment. However, its association with bacterial infections remains unclear.

objectivesTo investigate the associations of clinical and ultrasonographic findings, particularly consolidation depth, with opportunistic bacterial infections (OBI), viral infections, or Mycoplasma bovis (also known as Mycoplasmopsis bovis) infections. Different definitions of OBI were explored, based on various combinations of bacterial species, with or without a neutrophilic profile on cytology. ANIMALS: Eighty-six group-housed calves with at least one clinical sign of respiratory disease from 19 herds experiencing a respiratory epidemic.

methodsCross-sectional study. A physical examination, TUS, and non-bronchoscopic bronchoalveolar lavage were performed. The definitions of OBI were based on semi-quantitative culture results and cytology.

resultsCalves with consolidations of ≥ 0.5 cm had higher odds of having an OBI considering most definitions, on M. bovis isolation (odds ratio [OR] = 57.3; 95% confidence interval [CI] = 1.5-2300; p = 0.03) and isolation of a bacterial agent in general (OR = 15.5; 95% CI = 2.3-100; p = 0.01). Animals with consolidation ≥ 1 cm had higher odds of OBI considering all definitions, virus isolation (OR = 15.6; 95% CI = 1.0-240; p = 0.05) and isolation of a bacterial agent in general (OR = 6.9; 95% CI = 1.7-28; p = 0.01). Consolidation ≥ 3 cm, cough, and the California score were not significantly associated with OBI, M. bovis, or both.

conclusionIn herds experiencing a respiratory epidemic, consolidation depths ≥ 0.5 and ≥ 1 cm might indicate respiratory disease with a bacterial component.

Indexed as

Bronchoalveolar Lavage FluidCattle DiseasesLungRespiratory Tract InfectionsAnimalsBacterial InfectionsCattleCross-Sectional StudiesFemaleMaleMycoplasma bovisUltrasonographyVirus Diseasesbovine respiratory diseasecytologypneumoniarational antimicrobial usethoracic ultrasound

Identifiers

PMID40401500
PMCPMC12096172

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.