Evidence map›Paper›PMID 40401398›Full record

Trial reportStroke2025

Biofeedback Training for 3-Dimensional Finger Force Control to Improve Upper Limb Function Poststroke: An RCT.

Na Jin Seo, Christian Schranz, Kristen Coupland, Jenna Blaschke, Gabrielle Scronce, Christian Finetto, Adam Baker, Ja'Quann Gallant, Arianna Alston, Keith Howard and 4 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Stroke, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03995069 (Novel Training Environment to Normalize Altered Finger Force Direction Post Stroke), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03995069 nacompletednot on this map

Novel Training Environment to Normalize Altered Finger Force Direction Post Stroke

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2020 to 2024Enrolled51ConditionsStrokeArms3D, 1D
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Na Jin SeoRalph H. Johnson Veterans Affairs Health Care System, Charleston, SC (N.J.S., C.S., K.C., J.B., G.S., C.F., A.B., J.G., A.A., K.H., D.T., V.R.).ORCID 0000-0001-6446-5905
Christian SchranzRalph H. Johnson Veterans Affairs Health Care System, Charleston, SC (N.J.S., C.S., K.C., J.B., G.S., C.F., A.B., J.G., A.A., K.H., D.T., V.R.).ORCID 0000-0003-1102-7180
Kristen CouplandRalph H. Johnson Veterans Affairs Health Care System, Charleston, SC (N.J.S., C.S., K.C., J.B., G.S., C.F., A.B., J.G., A.A., K.H., D.T., V.R.).
Jenna BlaschkeRalph H. Johnson Veterans Affairs Health Care System, Charleston, SC (N.J.S., C.S., K.C., J.B., G.S., C.F., A.B., J.G., A.A., K.H., D.T., V.R.).ORCID 0000-0003-3785-3472
Gabrielle ScronceRalph H. Johnson Veterans Affairs Health Care System, Charleston, SC (N.J.S., C.S., K.C., J.B., G.S., C.F., A.B., J.G., A.A., K.H., D.T., V.R.).ORCID 0000-0002-3861-1371
Christian FinettoRalph H. Johnson Veterans Affairs Health Care System, Charleston, SC (N.J.S., C.S., K.C., J.B., G.S., C.F., A.B., J.G., A.A., K.H., D.T., V.R.).ORCID 0000-0003-0520-2034
Adam BakerRalph H. Johnson Veterans Affairs Health Care System, Charleston, SC (N.J.S., C.S., K.C., J.B., G.S., C.F., A.B., J.G., A.A., K.H., D.T., V.R.).ORCID 0000-0002-7483-0360
Ja'Quann GallantRalph H. Johnson Veterans Affairs Health Care System, Charleston, SC (N.J.S., C.S., K.C., J.B., G.S., C.F., A.B., J.G., A.A., K.H., D.T., V.R.).ORCID 0009-0003-5200-4433
Arianna AlstonRalph H. Johnson Veterans Affairs Health Care System, Charleston, SC (N.J.S., C.S., K.C., J.B., G.S., C.F., A.B., J.G., A.A., K.H., D.T., V.R.).
Keith HowardRalph H. Johnson Veterans Affairs Health Care System, Charleston, SC (N.J.S., C.S., K.C., J.B., G.S., C.F., A.B., J.G., A.A., K.H., D.T., V.R.).ORCID 0009-0007-8604-9081
Devin ThompsonRalph H. Johnson Veterans Affairs Health Care System, Charleston, SC (N.J.S., C.S., K.C., J.B., G.S., C.F., A.B., J.G., A.A., K.H., D.T., V.R.).ORCID 0000-0002-5224-1098
Viswanathan RamakrishnanRalph H. Johnson Veterans Affairs Health Care System, Charleston, SC (N.J.S., C.S., K.C., J.B., G.S., C.F., A.B., J.G., A.A., K.H., D.T., V.R.).ORCID 0000-0002-4098-0539
Christine A HolmstedtDepartment of Neurology (C.A.H.), Medical University of South Carolina, Charleston.ORCID 0000-0001-5269-9632
Derek G KamperLampe Joint Department of Biomedical Engineering, North Carolina State University, University of North Carolina at Chapel Hill, Raleigh (D.G.K.).ORCID 0000-0001-9048-4106

Funding

Treating Depression and Enhancing Locomotor Recovery Post-strokeP20GM109040 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KAUTZ, STEVEN A. · 2014 to 2024
$23.5M
NIGMS NIH HHS P20 GM109040RRD VA I01 RX003066
6 · The paper itself

Abstract

backgroundAfter stroke, impairment of hand sensorimotor control leads to improperly scaled and directed fingertip forces that disrupt object manipulation. The objective of this study was to determine the efficacy of finger force magnitude and direction training using 3-dimensional versus 1-dimensional biofeedback to enhance poststroke upper extremity motor recovery.

methodsA double-blind randomized controlled trial took place in the Veterans Affairs laboratory from 2020 to 2023. Forty-five stroke survivors were randomly assigned to the experimental or control group. Both groups received 18 training sessions to generate digit force in the target magnitude and direction. The experimental group trained with visual feedback on the digit force magnitude in 3 dimensions. The control group trained with 1-dimensional visual feedback on the digit force magnitude along the target direction only. The primary outcome was the change in upper extremity function assessed using the Action Research Arm Test post-intervention.

resultsBaseline characteristics were comparable between the groups (mean age, 59 years, 60% male, 40% Black people). The change between pretraining and posttraining Action Research Arm Test scores was significantly greater for the experimental group than for the control group (experimental mean, 3.5 [CI, 2.2-4.8] versus control mean, 0.8 [CI, -0.5 to 2.1];

conclusionsForce direction feedback led to improved upper extremity motor recovery in stroke survivors. This biofeedback-based treatment may provide the needed explicit training in force direction control for more effective hand rehabilitation. REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT03995069.

Indexed as

Biofeedback, PsychologyFingersStrokeStroke RehabilitationUpper ExtremityAgedDouble-Blind MethodFeedback, SensoryFemaleHand StrengthHumansMaleMiddle AgedRecovery of Functionbiomechanical phenomenafeedback, sensorymotor disordersmotor skillspsychomotor performancestroke rehabilitationupper extermity

Identifiers

PMID40401398
PMCPMC12303752

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.