Evidence map›Paper›PMID 40401395›Full record

ArticleAnnals of surgery2025

"What's a Win": A Qualitative Study Exploring Surgeon Perspectives on Operative Intent in Non-curative Cancer Surgery.

Orly N Farber, Amanda J Reich, Kenneth Williams, Zara Cooper, Jennifer W Mack, George Q Zhang, Tatiana Ramos, Elizabeth J Lilley

Abstract read
In one paragraph

Article in Annals of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Orly N FarberDepartment of Surgery, Brigham and Women's Hospital, Boston, MA, USA.ORCID 0000-0002-0615-2641
Amanda J ReichCenter for Surgery and Public Health at Brigham and Women's Hospital, Boston, MA, USA.
Kenneth WilliamsCenter for Surgery and Public Health at Brigham and Women's Hospital, Boston, MA, USA.
Zara CooperDepartment of Surgery, Brigham and Women's Hospital, Boston, MA, USA.
Jennifer W MackDepartment of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute, Boston, MA, USA.
George Q ZhangDepartment of Surgery, Brigham and Women's Hospital, Boston, MA, USA.
Tatiana RamosCenter for Surgery and Public Health at Brigham and Women's Hospital, Boston, MA, USA.
Elizabeth J LilleyDepartment of Surgery, Brigham and Women's Hospital, Boston, MA, USA.ORCID 0000-0002-3617-9829

Funding

Training Program in Cancer EpidemiologyT32CA009001 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI A. Heather Eliassen, Meir Stampfer · 1985 to 2026
$17.3M
RESEARCH TRAINING IN ALIMENTARY TRACT SURGERYT32DK007754 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI HODIN, RICHARD A. · 1997 to 2025
$6.5M
Mentored Research Training in Aging and Surgery (MERITAS)R38AG085422 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI Zara R Cooper, Louis Loc Nguyen · 2024 to 2026
$1.0M
NCI NIH HHS T32 CA009001NIA NIH HHS R38 AG085422NIDDK NIH HHS T32 DK007754
6 · The paper itself

Abstract

objectiveTo explore surgeons' perspectives on and priorities for communicating about non-curative operations for patients with advanced cancers, which aim to improve longevity or quality of life without possibility of cure. SUMMARY BACKGROUND DATA: Describing the potential benefits of non-curative surgery is important so that treatment decisions are based on an accurate understanding of what surgery can achieve. However, surgeons' perspectives on and practices for communicating non-curative operative intent with patients are not known.

methodsThis qualitative study involved semi-structured interviews with cancer surgeons who were recruited throughout the U.S. through purposive and snowball sampling. Interviews included discussions around two case scenarios describing non-curative operations. We explored participants' perspectives and communication preferences through the scenarios. Thematic analysis was completed using an inductive approach.

resultsWe interviewed 18 surgeons from 16 institutions with varying years of practice. Surgeons framed the overarching goal of non-curative surgery as preventing disease progression, with the more specific goals of living longer and living better. Additionally, participants underscored the prognostic uncertainty about the disease trajectory of advanced cancer, compounded by limited evidence to guide decisions about non-curative surgery. This uncertainty informs surgeons' communication priorities to 1) clarify treatment intent and 2) disclose their uncertainty, ultimately aiming to establish alignment with their patients.

conclusionsThis study delineated an existing paradigm for discussing the goals of non-curative surgery for advanced cancer, and also highlighted the role that prognostic uncertainty plays in cancer surgeons' communication practices.

Indexed as

communicationcurativeincurablemetastaticnon-curativeoperative intentpalliativequalitativetreatment intentuncertainty

Identifiers

PMID40401395
PMCPMC12718607

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.