Evidence map›Paper›PMID 40401378›Full record

Observational studyClinical & experimental ophthalmology

Normative Values on Stromal Curvature, Power and Corneal-Stromal Curvature Ratios From a Hybrid AS-OCT.

Jascha A Wendelstein, Arianna Grendele, Achim Langenbucher, Alice Galzignato, Catarina Praefke Coutinho, Seth Pantanelli, Kamran M Riaz, Giacomo Savini

Abstract readObservational Study
In one paragraph

Observational study in Clinical & experimental ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jascha A WendelsteinUniversity Eye Hospital, Ludwig-Maximilians-University, Munich, Germany.ORCID 0000-0003-4145-2559
Arianna GrendeleStudio Oculistico d'Azeglio, Bologna, Italy.
Achim LangenbucherInstitute of Experimental Ophthalmology, Saarland University, Homburg, Germany.
Alice GalzignatoStudio Oculistico d'Azeglio, Bologna, Italy.
Catarina Praefke CoutinhoStudio Oculistico d'Azeglio, Bologna, Italy.
Seth PantanelliDepartment of Ophthalmology, Penn State College of Medicine, Hershey, Pennsylvania, USA.ORCID 0000-0003-4992-9606
Kamran M RiazDean A. McGee Eye Institute/University of Oklahoma, Oklahoma City, Oklahoma, USA.ORCID 0000-0003-1090-5025
Giacomo SaviniIRCCS Bietti Foundation, Rome, Italy.

Funding

Fondazione RomaItalian Ministry of Health
6 · The paper itself

Abstract

backgroundTo establish normative values for stromal curvature and its relationships to anterior and posterior curvature.

methodsRetrospective observational study. Data were obtained from 75 eyes of cataract surgery patients using a high-resolution anterior segment optical coherence tomograph (AS-OCT; MS-39, CSO). Data analysis included anterior, stromal, and posterior curvature across multiple zones (1.0-5.0 mm), and derived curvature ratios.

resultsThe anterior-to-stromal curvature ratio (ASR) remained stable (1.016-1.007), while the stromal-to-posterior (SPR) and anterior-to-posterior (APR) ratios exhibited trends of slight change (SPR: 1.149-1.167; APR: 1.167-1.175). The refractive power analysis revealed incremental effects across one, two, and three refractive surface models, emphasising the importance of integrating posterior and stromal curvature data into optical assessments.

conclusionThis study provides the first normative values for stromal curvature and its ratios with anterior and posterior curvature. These findings may have implications for corneal- and lens-based surgeries and diagnostics.

Indexed as

Corneal StromaRefraction, OcularTomography, Optical CoherenceAgedAged, 80 and overCorneal TopographyFemaleHumansMaleMiddle AgedReference ValuesRetrospective StudiesVisual Acuityanterior curvaturecorneal radiuscurvature ratioposterior curvaturestromal curvature

Identifiers

PMID40401378
PMCPMC12516649

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.