ArticleJournal of food science2025
Multiresponse Surface Optimization of Ionic Gelation Vibrational Jet Flow Technology to Fine-Tune Kafirin Microparticles Extracted From Sorghum Dried Distiller's Grain.
Article in Journal of food science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Sorghum dried distiller's grain with solubles (DDGS), a protein-enriched byproduct of sorghum bioethanol production, is predominantly used as a low-cost animal feed. However, unutilized DDGS is mainly discarded as waste, containing approximately 40% of the prolamin protein kafirin. Kafirin's high hydrophobicity, low digestibility, evaporation-induced self-assembly, and strong disulfide cross-linking offer potential for biomaterial applications. This study used ethanol extraction and acid precipitation to purify kafirin protein from sorghum DDGS. The extracted protein was then used to prepare microparticles using ionic gelation vibrational jet flow technology (IGVJFT). This technology enables reproducible, uniform, scalable, high-speed microparticle production compared to existing methodologies. The integrated electrode voltage (V), internal frequency/vibration (Hz), and DDGS kafirin concentration (% [w/v]) used in the IGVJFT process were evaluated against key microparticle physicochemical response factors of volume-weighted mean microparticle size (% [w/v]), zeta potential (mV), and fracture frequency (mechanical strength) (%). Optimization of microparticle formation was performed by a response surface methodology (RSM) central composite design. Under different processing parameters of the RSM, the resulting DDGS kafirin microparticles possessed spherical morphology, volume-weighted mean particle sizes from 406.7 to 656.4 µm, zeta potential in the range of -38.2 to -18.1 mV, and fracture frequency (mechanical strength) of 23%-57%. Optimal conditions for producing microparticles with minimal size, high negative zeta potential, and low fracture frequency were identified and validated. These findings highlight the potential of DDGS kafirin as a sustainable material for large-scale microparticle applications and demonstrate the efficacy of IGVJFT for assembling hydrophobic proteins into microparticles with tailored physicochemical properties.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.