Evidence map›Paper›PMID 40401321›Full record

Trial reportSuicide & life-threatening behavior2025

THRIVE: Feasibility, Acceptability, and Social Validity of a Brief Recovery-Focused Intervention in Crisis Stabilization Centers.

Jennifer D Lockman, Anthony R Pisani, Breanna P Angerer, Adam C Graham, Jacob Henry, Fallan Lloyd

Registry-linked trialAbstract readRandomized Controlled TrialValidation Study
In one paragraph

Trial report in Suicide & life-threatening behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05558891 (THRIVE), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05558891 nacompletednot on this map

THRIVE: Pilot Study of a Brief, Recovery-focused Intervention for Crisis Stabilization Centers

TypeinterventionalSponsorCenterstone Research InstituteRan2022 to 2024Enrolled137ConditionsSuicideArmsTHRIVE, Usual Care
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jennifer D LockmanDepartment of Psychiatry and Behavioral Neurobiology, Depression and Suicide Center, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID https://orcid.org/0000-0002-0723-8439
Anthony R PisaniDepartment of Psychiatry, Center for the Study and Prevention of Suicide, University of Rochester, Rochester, New York, USA.ORCID https://orcid.org/0000-0003-4698-8432
Breanna P AngererDepartment of Psychiatry and Behavioral Neurobiology, Depression and Suicide Center, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Adam C GrahamTBD Solutions, Inc., Grand Rapids, Michigan, USA.
Jacob HenryEllie Mental Health, Nashville, Tennessee, USA.
Fallan LloydDepartment of Psychiatry and Behavioral Neurobiology, Depression and Suicide Center, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Funding

American Foundation for Suicide Prevention YIG-0-113-20
6 · The paper itself

Abstract

backgroundCrisis Stabilization Centers (CSCs) are a critical component of the crisis response system and the 988 Lifeline expansion that may promote ED diversion. To maximize CSC care quality and effectiveness, brief psychotherapy interventions that focus on recovery, match CSC workflows, and have the potency to reduce suicide attempts and deaths are needed but do not exist. The purpose of this study was to establish the feasibility, acceptability, appropriateness, and social validity of a novel, ultra-brief, 60-min psychotherapy intervention-Toward Hope, Recovery, Interpersonal Connection, Values, and Engagement for Crisis (THRIVE-C).

methodsWe recruited CSC stakeholders (n = 15) and CSC study therapists (n = 5) to complete surveys, followed by a pilot study of THRIVE-C with CSC guests (n = 54).

resultsCSC stakeholders, study therapists, and guests found THRIVE feasible, acceptable, appropriate, and socially valid. CSC guests experienced THRIVE-C as satisfactory, established a positive therapeutic alliance (bond), and 91% of guests endorsed behavioral intentions to attend outpatient psychotherapy appointments after discharge. Further, 94% of guests completed all phases of THRIVE, demonstrating clinical readiness to work on suicide recovery beyond physical safety or stabilization from suicide alone.

conclusionPreliminary findings suggest that further development and testing of THRIVE are needed.

trial registrationThis study was registered with ClinicalTrials.gov (Identifier NCT05558891).

Indexed as

Crisis InterventionPsychotherapy, BriefAdultFeasibility StudiesFemaleHumansMaleMiddle AgedPilot Projectscrisis stabilization centersinterpersonal theory of suicidesuicide care engagementsuicide preventionsuicide recoveryTHRIVE

Identifiers

PMID40401321
PMCPMC12096272

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.