ArticleFrontiers in cardiovascular medicine2025
Impedance cardiography parameters reflecting left ventricular function are markers of pulmonary arterial hypertension.
Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Mobile Application for Visualization and Analysis of Impedance Cardiography Signals.Medical devices (Auckland, N.Z.) · 2025Article
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5 authors.
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Abstract
Background: Pre-capillary pulmonary hypertension (PH) is characterized by pulmonary vascular remodeling and right heart failure. We aim to identify impedance cardiography (ICG) parameters with potential for pre-capillary PH screening and prognostic prediction. Methods: A discovery cohort consisting of 26 patients with pulmonary arterial hypertension (PAH) and 20 healthy volunteers was enrolled from August 2018 to March 2019. Another 100 patients who had undergone right heart catheterization (RHC) due to suspected PAH were enrolled from April 2019 to August 2020 as the validation cohort. In total, 62 patients with pre-capillary PH in the discovery and validation cohorts were followed up for 41 months. The relationships between ICG parameters and pre-capillary PH screening and prognostic prediction were studied. Results: Patients with pre-capillary PH exhibited lower left ventricular stroke work (LSW) and left ventricular stroke work index (LSWI) values compared to the healthy controls, which was further proved in the validation cohort [51.5 (41.8-67.2) vs. 69.7 (68.1-72.3) g·m/beat, Conclusion: LSW and LSWI detected by ICG are useful in pre-capillary PH screening and valuable as long-term predictors of clinical worsening in pre-capillary PH treatment.
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