Evidence map›Paper›PMID 40401220›Full record

ArticleFrontiers in cardiovascular medicine2025

Efficacy and safety of leadless pacemaker implantation in octogenarians: a single-center experience.

Zhipeng Zhang, Zonglei Wu, Chao Luan, Shiyu Dai, FeiFei Chen, Yuchen Gao, Fenglan Huang, Yuanjun Sun, Xiaomeng Yin, Lianjun Gao and 2 more

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhipeng ZhangDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Zonglei WuDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Chao LuanDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Shiyu DaiDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
FeiFei ChenDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Yuchen GaoDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Fenglan HuangDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Yuanjun SunDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Xiaomeng YinDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Lianjun GaoDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Jinqiu LiuDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Xiaohong YuDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Long-term complications occur in approximately 4%-12% of patients with standard transvenous pacemakers (TVPs), most of whom are elderly. The leadless pacemaker (LP) has emerged as an effective alternative to traditional TVPs, offering a lower complication profile. However, data on LP implantation in octogenarians remain limited, and concerns persist regarding its feasibility and safety in this population. This study aimed to assess the feasibility and clinical outcomes of LP implantation in octogenarians. Methods and Results: Between January 2021 and January 2024, 154 patients (mean age 75.5 ± 9.8 years) who underwent LP implantation at our center were consecutively included. The study cohort was stratified into two age groups: octogenarians (≥80 years, mean age 84.2 ± 3.3 years, Conclusions: LP implantation appears to be a safe and effective therapeutic option for octogenarians, including those with more combabilities. Therefore, it should be considered a viable alternative to conventional TVPs in this aging population.

Indexed as

complicationefficacy and safetyleadless pacemakeroctogenarianspacing induced cardiomyopathy

Identifiers

PMID40401220
PMCPMC12092340

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.