Evidence map›Paper›PMID 40401157›Full record

ArticleFrontiers in microbiomes2024

Diet-Microbiome Interactions Influence Lung Function in Chronic Obstructive Pulmonary Disease.

Haowen Qiu, Rees Checketts, Mariah Kay Jackson, Jean-Jack M Riethoven, Nadia N Hansel, Kristina L Bailey, Corrine Hanson, Derrick R Samuelson

Abstract read
In one paragraph

Article in Frontiers in microbiomes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Haowen QiuBioinformatics Core Research Facility, Nebraska Center for Biotechnology, University of Nebraska-Lincoln, Lincoln, NE, USA.
Rees CheckettsDepartment of Internal Medicine, Internal Medicine Residency Program, Creighton University Medicine Center, Omaha, NE, USA.
Mariah Kay JacksonDepartment of Medical Sciences, Medical Nutrition Education Program, University of Nebraska Medical Center, Omaha, NE, USA.
Jean-Jack M RiethovenBioinformatics Core Research Facility, Nebraska Center for Biotechnology, University of Nebraska-Lincoln, Lincoln, NE, USA.
Nadia N HanselDepartment of Medicine, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., USA.
Kristina L BaileyDepartment of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep, University of Nebraska Medical Center, Omaha, NE, USA.
Corrine HansonDepartment of Medical Sciences, Medical Nutrition Education Program, University of Nebraska Medical Center, Omaha, NE, USA.
Derrick R SamuelsonDepartment of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep, University of Nebraska Medical Center, Omaha, NE, USA.

Funding

UNMC Structural Biology CoreP20GM103427 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Heather Colleen Jensen-Smith · 2012 to 2026
$59.2M
UNMC/EPPLEY CANCER CENTER SUPPORT GRANTP30CA036727 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI James Eudy · 1985 to 2026
$55.0M
Gut bacterial metallophores in the development and severity of inflammatory bowel diseaseR01DK131990 · NIDDK · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Derrick R Samuelson · 2022 to 2026
$3.3M
Mechanisms by Which Alcohol-Induced Dysbiosis Impairs Host Defense Against Klebsiella PneumoniaeR00AA026336 · NIAAA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI SAMUELSON, DERRICK R · 2019 to 2021
$743k
BLRD VA I01 BX006049NCI NIH HHS P30 CA036727NIAAA NIH HHS R00 AA026336NIDDK NIH HHS R01 DK131990NIGMS NIH HHS P20 GM103427
6 · The paper itself

Abstract

Chronic Obstructive Pulmonary Disease (COPD) affects 30 million Americans. Previous epidemiologic work has shown that diet can impact pulmonary function in those with and without COPD. Diet is also a major driver of gut microbiome composition and function. Importantly, the gut microbiome has also been associated with lung health (i.e., the gut-lung axis) in both preclinical and clinical studies. Despite this growing body of evidence, many questions remain regarding the gut-lung axis. Specifically, how the microbiome impacts the relationship between diet factors and spirometry or stage of disease in people with COPD is little understood. We hypothesize that there are taxonomic differences in the gut microbiome among the different stages of COPD and that diet microbiome interactions influence pulmonary function. This study aimed to identify how the GI microbiota correlated with the severity of respiratory disease in COPD patients and how the microbiome may mediate the relationship between diet, including fiber and omega-3 fatty acids, and lung function outcomes.

Indexed as

COPDDietFiberLungsMicrobiomeOmega-3 Fatty Acid

Identifiers

PMID40401157
PMCPMC12094515

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.