ArticleFrontiers in public health2025
Long-term PM2.5 exposure and new-onset lung diseases among middle-aged and older adults in China: a retrospective cohort study from CHARLS.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Air pollution caused by ambient fine particulate matter (≤ 2.5 μm) adversely affects human health. Previous studies have shown that PM2.5 exposure increases the risk of lung diseases. However, the relationship between long-term PM2.5 exposure and new-onset lung diseases among middle-aged and older adults in China is still unclear. Methods: We conducted a retrospective cohort study through the China Health and Retirement Longitudinal Study (CHARLS) and Science Data Bank (ScienceDB). The logistic regression model and restricted cubic spline (RCS) were used to explore the relationship between long-term PM2.5 exposure and new-onset lung diseases. To further increase the robustness of the results, we performed sensitivity and subgroup analyses. Results: A total of 10,707 patients were included in this study. The 10,707 patients were divided into two groups: without new-onset lung diseases ( Conclusion: PM2.5 exposure increases the risk of new-onset lung diseases among middle-aged and old adults in China, especially when the concentration of PM2.5 > 48.5 ug/m
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